1PEZ
 
 | | Bacillus circulans strain 251 mutant A230V | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETIC ACID, ... | | 著者 | Rozeboom, H.J, Dijkstra, B.W. | | 登録日 | 2003-05-23 | | 公開日 | 2003-10-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Conversion of Cyclodextrin Glycosyltransferase into a Starch Hydrolase by Directed Evolution: The Role of Alanine 230 in Acceptor Subsite +1
Biochemistry, 42, 2003
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7P8I
 | | Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | 著者 | Scietti, L, Castelli, M, Faravelli, S, Clementi, N, Mancini, N, Forneris, F. | | 登録日 | 2021-07-22 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Evidence of SARS-CoV-2 Direct Evolution in R. affinis Bats Driven by Affinity and Dynamics Optimization of the Spike Protein
To Be Published
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5KR4
 | | Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | | 分子名称: | 1,2-ETHANEDIOL, 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | | 登録日 | 2016-07-06 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19, 2017
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5KR6
 | | Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | | 分子名称: | 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | | 登録日 | 2016-07-07 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19, 2017
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5KQU
 | | Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | | 分子名称: | 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | | 登録日 | 2016-07-06 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19, 2017
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7DCL
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5D2W
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6LDF
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6LDE
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6LDG
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6DKV
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6DC1
 | | Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-nitro-2-oxidanyl-benzenecarbonitrile, ... | | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
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6DNJ
 | | Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 28 round 5 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1,2-benzoxazole, Kemp eliminase KE07 | | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | | 登録日 | 2018-06-06 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
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6CT3
 | | Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 27 round 7-2 | | 分子名称: | 5-nitro-2-oxidanyl-benzenecarbonitrile, GLYCEROL, Kemp eliminase, ... | | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | | 登録日 | 2018-03-22 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
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5KQT
 | | Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | | 分子名称: | 4-aminoburyrate transaminase, CHLORIDE ION, GLYCEROL, ... | | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | | 登録日 | 2016-07-06 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19, 2017
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5KR3
 | | Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | | 分子名称: | 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | | 登録日 | 2016-07-06 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19, 2017
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5KQW
 | | Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | | 分子名称: | 1,2-ETHANEDIOL, 4-aminobutyrate transaminase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | | 登録日 | 2016-07-06 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19, 2017
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5KR5
 | | Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | | 分子名称: | 4-aminobutyrate transaminase, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | | 登録日 | 2016-07-07 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19, 2017
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6C7T
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6CAI
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6C8B
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6C7H
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6C7M
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6C7V
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6U18
 | | Directed evolution of a biosensor selective for the macrolide antibiotic clarithromycin | | 分子名称: | CITRATE ANION, CLARITHROMYCIN, Erythromycin resistance repressor protein | | 著者 | Li, Y, Reed, M, Wright, H.T, Cropp, T.A, Williams, G. | | 登録日 | 2019-08-15 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Development of Genetically Encoded Biosensors for Reporting the Methyltransferase-Dependent Biosynthesis of Semisynthetic Macrolide Antibiotics.
Acs Synth Biol, 2021
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