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5KQW

Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries

Summary for 5KQW
Entry DOI10.2210/pdb5kqw/pdb
Related5KQT 5KQU 5KR3 5KR4 5KR5 5KR6
Descriptor4-aminobutyrate transaminase, MAGNESIUM ION, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywordsphylogenetics, directed evolution, transaminase, protein engineering, transferase
Biological sourcePseudomonas
Total number of polymer chains4
Total formula weight209207.91
Authors
Wilding, M.,Newman, J.,Peat, T.S.,Scott, C. (deposition date: 2016-07-06, release date: 2017-07-12, Last modification date: 2023-10-04)
Primary citationWilding, M.,Peat, T.S.,Kalyaanamoorthy, S.,Newman, J.,Scott, C.,Jermiin, L.S.
Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19:5375-, 2017
Cited by
DOI: 10.1039/c7gc02343j
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.23 Å)
Structure validation

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