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5KR4

Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries

Summary for 5KR4
Entry DOI10.2210/pdb5kr4/pdb
Related5KQT 5KQU 5KQW 5KR3 5KR5 5KR6
Descriptor4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsphylogenetics, directed evolution, transaminase, protein engineering, transferase
Biological sourcePseudomonas
Total number of polymer chains2
Total formula weight104516.09
Authors
Wilding, M.,Newman, J.,Peat, T.S.,Scott, C. (deposition date: 2016-07-06, release date: 2017-07-12, Last modification date: 2023-10-04)
Primary citationWilding, M.,Peat, T.S.,Kalyaanamoorthy, S.,Newman, J.,Scott, C.,Jermiin, L.S.
Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
Green Chemistry, 19:5375-, 2017
Cited by
DOI: 10.1039/c7gc02343j
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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