5KR4
Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries
Summary for 5KR4
Entry DOI | 10.2210/pdb5kr4/pdb |
Related | 5KQT 5KQU 5KQW 5KR3 5KR5 5KR6 |
Descriptor | 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | phylogenetics, directed evolution, transaminase, protein engineering, transferase |
Biological source | Pseudomonas |
Total number of polymer chains | 2 |
Total formula weight | 104516.09 |
Authors | Wilding, M.,Newman, J.,Peat, T.S.,Scott, C. (deposition date: 2016-07-06, release date: 2017-07-12, Last modification date: 2023-10-04) |
Primary citation | Wilding, M.,Peat, T.S.,Kalyaanamoorthy, S.,Newman, J.,Scott, C.,Jermiin, L.S. Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction Green Chemistry, 19:5375-, 2017 Cited by DOI: 10.1039/c7gc02343jPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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