6C7H
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 18 Design Trp50Ala mutant
Summary for 6C7H
Entry DOI | 10.2210/pdb6c7h/pdb |
Descriptor | Kemp eliminase KE07 (2 entities in total) |
Functional Keywords | kemp eliminase, directed evolution, ke07, de novo protein, lyase |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 29044.28 |
Authors | Jackson, C.J.,Hong, N.-S.,Carr, P.D. (deposition date: 2018-01-22, release date: 2018-08-01, Last modification date: 2023-10-04) |
Primary citation | Hong, N.S.,Petrovic, D.,Lee, R.,Gryn'ova, G.,Purg, M.,Saunders, J.,Bauer, P.,Carr, P.D.,Lin, C.Y.,Mabbitt, P.D.,Zhang, W.,Altamore, T.,Easton, C.,Coote, M.L.,Kamerlin, S.C.L.,Jackson, C.J. The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9:3900-3900, 2018 Cited by PubMed: 30254369DOI: 10.1038/s41467-018-06305-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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