7P8I

Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 1

Summary for 7P8I

• Entry DOI: 10.2210/pdb7p8i/pdb
• Descriptor: Processed angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: covid-19 bat coronavirus spillover zoonotic viral infection evolution, immune system, cell invasion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 196260.67

Authors

Scietti, L.,Castelli, M.,Faravelli, S.,Clementi, N.,Mancini, N.,Forneris, F. (deposition date: 2021-07-22, release date: 2022-08-03, Last modification date: 2024-11-06)

• Primary citation: Castelli, M.,Scietti, L.,Faravelli, S.,Clementi, N.,Forneris, F.,Mancini, N.; Evidence of SARS-CoV-2 Direct Evolution in R. affinis Bats Driven by Affinity and Dynamics Optimization of the Spike Protein; To Be Published,

Experimental method

X-RAY DIFFRACTION (4.5 Å)