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6C8B

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 23 round 6

Summary for 6C8B
Entry DOI10.2210/pdb6c8b/pdb
DescriptorKemp eliminase KE07 (2 entities in total)
Functional Keywordskemp eliminase, directed evolution, ke07, de novo protein, lyase
Biological sourcesynthetic construct
Total number of polymer chains2
Total formula weight58536.68
Authors
Jackson, C.J.,Hong, N.-S.,Carr, P.D. (deposition date: 2018-01-24, release date: 2018-08-01, Last modification date: 2023-10-04)
Primary citationHong, N.S.,Petrovic, D.,Lee, R.,Gryn'ova, G.,Purg, M.,Saunders, J.,Bauer, P.,Carr, P.D.,Lin, C.Y.,Mabbitt, P.D.,Zhang, W.,Altamore, T.,Easton, C.,Coote, M.L.,Kamerlin, S.C.L.,Jackson, C.J.
The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9:3900-3900, 2018
Cited by
PubMed: 30254369
DOI: 10.1038/s41467-018-06305-y
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.61 Å)
Structure validation

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