6CAI

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 24 round 7

Summary for 6CAI

Entry DOI	10.2210/pdb6cai/pdb
Descriptor	Kemp Eliminase KE07, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
Functional Keywords	kemp eliminase, directed evolution, ke07, de novo protein, lyase
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	58488.65
Authors	Jackson, C.J.,Hong, N.-S.,Carr, P.D. (deposition date: 2018-01-30, release date: 2018-08-01, Last modification date: 2023-10-04)
Primary citation	Hong, N.S.,Petrovic, D.,Lee, R.,Gryn'ova, G.,Purg, M.,Saunders, J.,Bauer, P.,Carr, P.D.,Lin, C.Y.,Mabbitt, P.D.,Zhang, W.,Altamore, T.,Easton, C.,Coote, M.L.,Kamerlin, S.C.L.,Jackson, C.J. The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9:3900-3900, 2018 Cited by PubMed: 30254369 DOI: 10.1038/s41467-018-06305-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation