6DKV

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 21 round 5

Summary for 6DKV

Entry DOI	10.2210/pdb6dkv/pdb
Descriptor	Kemp eliminase KE07, DI(HYDROXYETHYL)ETHER, 5-nitro-2-oxidanyl-benzenecarbonitrile, ... (4 entities in total)
Functional Keywords	kemp eliminase, directed evolution, ke07, de novo protein, lyase
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	29704.90
Authors	Jackson, C.J.,Hong, N.-S.,Carr, P.D. (deposition date: 2018-05-30, release date: 2018-08-01, Last modification date: 2023-10-11)
Primary citation	Hong, N.S.,Petrovic, D.,Lee, R.,Gryn'ova, G.,Purg, M.,Saunders, J.,Bauer, P.,Carr, P.D.,Lin, C.Y.,Mabbitt, P.D.,Zhang, W.,Altamore, T.,Easton, C.,Coote, M.L.,Kamerlin, S.C.L.,Jackson, C.J. The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9:3900-3900, 2018 Cited by PubMed: 30254369 DOI: 10.1038/s41467-018-06305-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation