6DKV

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 21 round 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue PEG A 301

Chain	Residue
A	GLU161
A	HOH495

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site_id	AC2
Number of Residues	12
Details	binding site for residue PEG A 302

Chain	Residue
A	HOH401
A	HOH428
A	HOH453
A	HOH464
A	HOH492
A	TRP50
A	GLY82
A	ASN103
A	THR104
A	TYR143
A	SER144
A	6VP303

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site_id	AC3
Number of Residues	11
Details	binding site for residue 6VP A 303

Chain	Residue
A	TRP50
A	GLU101
A	ASN103
A	TYR128
A	ARG202
A	LYS222
A	PEG302
A	HOH404
A	HOH415
A	HOH453
A	HOH560

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