8T7K
 
 | | Apo HftA from Treponema denticola | | 分子名称: | Pathogen-specific surface antigen, putative | | 著者 | Corbett, B.W, Suits, M.D. | | 登録日 | 2023-06-20 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural and functional characterization of the high-affinity ferrous iron transport protein HftA from Treponema denticola.
To Be Published
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8T7J
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8T7I
 | | Structure of the S1CE variant of Fab F1 (FabS1CE-F1) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, S1CE variant of Fab F1 heavy chain, ... | | 著者 | Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-06-20 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
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8T7H
 | | Quis-bound intermediate mGlu5 | | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Metabotropic glutamate receptor 5, Nanobody 43 | | 著者 | Krishna Kumar, K, Wang, H, Kobilka, B.K. | | 登録日 | 2023-06-20 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Stepwise activation of a metabotropic glutamate receptor.
Nature, 629, 2024
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8T7G
 | | Structure of the CK variant of Fab F1 (FabC-F1) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CK variant of Fab F1 heavy chain, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-06-20 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
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8T7F
 | | Structure of the S1 variant of Fab F1 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S1 variant of Fab F1 heavy chain, S1 variant of Fab F1 light chain, ... | | 著者 | Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-06-20 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
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8T7E
 | | Cryo-EM structure of the Backtracking Initiation Complex (VII) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-06-20 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8T7C
 | | Crystal structure of human phospholipase C gamma 2 | | 分子名称: | 1,2-ETHANEDIOL, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION | | 著者 | Chen, Y, Choi, H, Zhuang, N, Hu, L, Qian, D, Wang, J. | | 登録日 | 2023-06-20 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition
To Be Published
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8T7B
 | | Sequence specific (AATT) orientation of netropsin molecules at a unique minor groove binding site (position2) within a self-assembled 3D DNA lattice (4x5) | | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*TP*G)-3'), DNA (5'-D(P*AP*GP*GP*TP*CP*TP*GP*C)-3'), ... | | 著者 | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | | 登録日 | 2023-06-20 | | 公開日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals.
J.Am.Chem.Soc., 145, 2023
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8T7A
 | | Cryo-EM structure of RSV preF in complex with Fab 2.4K | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2.4K Fab Heavy Chain, 2.4K Fab Light Chain, ... | | 著者 | McCool, R.S, McLellan, J.S. | | 登録日 | 2023-06-20 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.
J.Virol., 97, 2023
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8T79
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 10 bp R-loop | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2023-06-20 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T78
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loop | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2023-06-19 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T77
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 6 bp R-loop | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2023-06-19 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T76
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 3 bp R-loop | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2023-06-19 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T75
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8T74
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8T73
 | | Crystal structure of KRAS4a-R151G with bound GDP and Mg ion | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K. | | 登録日 | 2023-06-19 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024
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8T72
 | | Crystal structure of WT KRAS4a with bound GMPPNP and Mg ion | | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K. | | 登録日 | 2023-06-19 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024
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8T71
 | | Crystal Structure of WT KRAS4a with bound GDP and Mg ion | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K. | | 登録日 | 2023-06-19 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024
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8T70
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8T6Z
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8T6Y
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loop | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2023-06-19 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6X
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loop | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2023-06-19 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6V
 | | Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ... | | 著者 | Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D. | | 登録日 | 2023-06-18 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
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8T6U
 | | Cryo-EM structure of human Anion Exchanger 1 bound to Dipyridamole | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D. | | 登録日 | 2023-06-18 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
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