8T7C

Crystal structure of human phospholipase C gamma 2

Summary for 8T7C

• Entry DOI: 10.2210/pdb8t7c/pdb
• Related: 8JQG 8JQH 8JQI
• Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: phospholipase c gamma 2, autoinhibition, signaling, lipid metabolism, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 136163.62

Authors

Chen, Y.,Choi, H.,Zhuang, N.,Hu, L.,Qian, D.,Wang, J. (deposition date: 2023-06-20, release date: 2024-06-26)

• Primary citation: Shin, Y.,Plummer, A.M.,Mungenast, A.,Choi, H.,TenDyke, K.,Zhu, X.,Shepard, J.,Zhuang, N.,Hu, L.,Qian, D.,Wang, J.,Poda, S.,Liao, M.,Chen, Y.; The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.55 Å)