8T7C
Crystal structure of human phospholipase C gamma 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | polymer | 1166 | 136061.5 | 1 | UniProt (P16885) Pfam (PF16457) Pfam (PF23329) Pfam (PF23583) Pfam (PF00388) Pfam (PF00017) Pfam (PF00018) Pfam (PF00387) Pfam (PF00168) | Homo sapiens (human) | Phosphoinositide phospholipase C-gamma-2,Phospholipase C-IV,PLC-IV,Phospholipase C-gamma-2,PLC-gamma-2 |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 14 - 221 (UniProt: P16885)
A: 239 - 1190 (UniProt: P16885)
| PDB | External Database | Details |
|---|---|---|
| Ser 11 | - | expression tag |
| Ile 12 | - | expression tag |
| Ala 13 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 222 | - | linker |
| Ser 223 | - | linker |
| Gly 224 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 136061.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 102.1 | |
| All* | Total formula weight | 136163.6 |






