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8T7C

Crystal structure of human phospholipase C gamma 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2polymer1166136061.51UniProt (P16885)
Pfam (PF16457)
Pfam (PF23329)
Pfam (PF23583)
Pfam (PF00388)
Pfam (PF00017)
Pfam (PF00018)
Pfam (PF00387)
Pfam (PF00168)
Homo sapiens (human)Phosphoinositide phospholipase C-gamma-2,Phospholipase C-IV,PLC-IV,Phospholipase C-gamma-2,PLC-gamma-2
2B
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D
(A)
waterwater18.0190Chemie (HOH)
Sequence modifications
A: 14 - 221 (UniProt: P16885)
PDBExternal DatabaseDetails
Ser 11-expression tag
Ile 12-expression tag
Ala 13-expression tag
A: 239 - 1190 (UniProt: P16885)
PDBExternal DatabaseDetails
Gly 222-linker
Ser 223-linker
Gly 224-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight136061.5
Non-Polymers*Number of molecules2
Total formula weight102.1
All*Total formula weight136163.6
*Water molecules are not included.

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PDB entries from 2026-02-25

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