PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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4GK0	Crystal structure of human Rev3-Rev7-Rev1 complex 分子名称: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Tao, J, Min, X, Wei, X. 登録日 2012-08-10 公開日 2013-03-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insights into the assembly of human translesion polymerase complexes Protein Cell, 3, 2012
1U47	cytosine-8-Oxoguanine base pair at the polymerase active site 分子名称: DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... 著者 Hsu, G.W, Ober, M, Carell, T, Beese, L.S. 登録日 2004-07-23 公開日 2004-09-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
3SI8	Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2) 分子名称: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ... 著者 Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W. 登録日 2011-06-17 公開日 2011-08-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
7CK5	Solution structure of 28 amino acid polypeptide (354-381) in Plantago asiatica mosaic virus replicase bound to SDS micelle 分子名称: PlAMV replicase peptide from RNA-dependent RNA polymerase 著者 Komatsu, K, Sasaki, N, Yoshida, T, Suzuki, K, Masujima, Y, Hashimoto, M, Watanabe, S, Tochio, N, Kigawa, T, Yamaji, Y, Oshima, K, Namba, S, Nelson, R, Arie, T. 登録日 2020-07-15 公開日 2021-07-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Identification of a Proline-Kinked Amphipathic alpha-Helix Downstream from the Methyltransferase Domain of a Potexvirus Replicase and Its Role in Virus Replication and Perinuclear Complex Formation. J.Virol., 95, 2021
4H63	Structure of the Schizosaccharomyces pombe Mediator head module 分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... 著者 Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. 登録日 2012-09-19 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure of the Mediator head module. Nature, 492, 2012
5YTD	large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the natural base pair 5fC:dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(5FC)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
5YTC	Large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the unnatural base M-fC pair with dATP in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(92F)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC)P*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
5ODD	HUMAN MED26 N-TERMINAL DOMAIN (1-92) 分子名称: Mediator of RNA polymerase II transcription subunit 26 著者 Lens, Z, Cantrelle, F.-X, Perruzini, R, Dewitte, F, Hanoulle, X, Villeret, V, Verger, A, Landrieu, I. 登録日 2017-07-05 公開日 2017-11-29 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26. Biomol.Nmr Assign., 10, 2016
6YP5	Solution NMR structure of the oligomerization domain of respiratory syncytial virus phosphoprotein 分子名称: Phosphoprotein 著者 Cardone, C, Bontems, F, Bardiaux, B, Sizun, C. 登録日 2020-04-15 公開日 2021-04-28 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein. Biomolecules, 11, 2021
5VU8	TNA polymerase, closed ternary complex 分子名称: DNA polymerase, DNA template, DNA/TNA hybrid primer, ... 著者 Chim, N, Chaput, J.C. 登録日 2017-05-18 公開日 2017-12-06 最終更新日 2017-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
4WKR	LaRP7 wrapping up the 3' hairpin of 7SK non-coding RNA (302-332) 分子名称: 7SK GGHP4 (300-332), La-related protein 7 著者 Uchikawa, E, Natchiar, K.S, Han, X, Proux, F, Roblin, P, Zhang, E, Durand, A, Klaholz, B.P, Dock-Bregeon, A.-C. 登録日 2014-10-03 公開日 2015-03-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7. Nucleic Acids Res., 43, 2015
1MFK	Structure of Prokaryotic SECIS mRNA Hairpin 分子名称: 5'-R(P*GP*GP*CP*GP*GP*UP*UP*GP*CP*AP*GP*GP*UP*CP*UP*GP*CP*AP*CP*CP*GP*CP*C)-3' 著者 Fourmy, D, Guittet, E, Yoshizawa, S. 登録日 2002-08-12 公開日 2002-11-13 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of Prokaryotic SECIS mRNA Hairpin and its Interaction with Elongation Factor SELB J.Mol.Biol., 324, 2002
8OJD	HSV-1 DNA polymerase beta-hairpin loop 分子名称: CALCIUM ION, DNA (47-MER), DNA (68-MER), ... 著者 Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. 登録日 2023-03-24 公開日 2024-04-03 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.46 Å) 主引用文献 Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
5VU7	TNA polymerase, open ternary complex 分子名称: 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... 著者 Chim, N, Chaput, J.C. 登録日 2017-05-18 公開日 2017-12-06 最終更新日 2017-12-13 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
2GWS	Crystal Structure of human DNA Polymerase lambda with a G/G mismatch in the primer terminus 分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*G)-3', ... 著者 Garcia-Diaz, M, Picher, A.J, Bebenek, K, Pedersen, L.C, Kunkel, T.A, Blanco, L. 登録日 2006-05-05 公開日 2006-09-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Promiscuous mismatch extension by human DNA polymerase lambda. Nucleic Acids Res., 34, 2006
5DQG	Crystal Structure of Human DNA Polymerase Eta Inserting dAMPNPP Opposite O4-Ethylthymidine 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-14 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
5DQH	Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Ethylthymidine 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-14 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
8DVO	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044 分子名称: 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-{[2-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2022-07-29 公開日 2022-09-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044 To Be Published
1WCL	NMR structure of the carboxyterminal domains of Escherichia coli NusA 分子名称: TRANSCRIPTION ELONGATION PROTEIN NUSA 著者 Eisenmann, A, Schwarz, S, Schweimer, K, Roesch, P. 登録日 2004-11-17 公開日 2005-08-31 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The E. Coli Nusa Carboxy-Terminal Domains are Structurally Similar and Show Specific Rnap- and Lambdan Interactions Protein Sci., 14, 2005
5DLF	Crystal Structure of Human DNA Polymerase Eta Inserting dATP Opposite O4-Methylhymidine 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-04 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
5TWQ	Post-catalytic nicked complex of human Polymerase Mu with newly incorporated UTP 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... 著者 Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. 登録日 2016-11-14 公開日 2017-07-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
5DLG	Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Methylhymidine 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5DB)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-04 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
2BCS	DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dcmp 分子名称: 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*CP*TP*AP*CP*TP*G)-3', 5'-D(*GP*CP*CP*G)-3', ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2005-10-19 公開日 2006-03-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124, 2006
2BCR	DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp 分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*AP*TP*AP*CP*TP*G)-3', ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2005-10-19 公開日 2006-03-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124, 2006
8DQS	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023032 分子名称: 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-2-[4-(trifluoromethyl)phenyl]-3,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2022-07-19 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023032 To Be Published

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