5YTC
Large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the unnatural base M-fC pair with dATP in the active site
Summary for 5YTC
Entry DOI | 10.2210/pdb5ytc/pdb |
Descriptor | DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC)P*(DOC))-3'), DNA (5'-D(*AP*AP*AP*(92F)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (6 entities in total) |
Functional Keywords | dna, replication, transferase-dna complex, transferase/dna |
Biological source | Thermus aquaticus More |
Total number of polymer chains | 3 |
Total formula weight | 70296.48 |
Authors | Zeng, H.,Mondal, M.,Song, R.Y.,Zhang, J.,Xia, B.,Yi, C.Q. (deposition date: 2017-11-17, release date: 2018-11-21, Last modification date: 2023-11-22) |
Primary citation | Zeng, H.,Mondal, M.,Song, R.,Zhang, J.,Xia, B.,Liu, M.,Zhu, C.,He, B.,Gao, Y.Q.,Yi, C. Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58:130-133, 2019 Cited by PubMed: 30407705DOI: 10.1002/anie.201807845 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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