5TWQ
Post-catalytic nicked complex of human Polymerase Mu with newly incorporated UTP
Summary for 5TWQ
| Entry DOI | 10.2210/pdb5twq/pdb |
| Related | 5TWP 5TWR 5TWS |
| Descriptor | human DNA Polymerase Mu, 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... (11 entities in total) |
| Functional Keywords | family x dna polymerase, nonhomologous end-joining, dna double strand break repair, ribonucleotide incorporation, transferase-dna complex, transferase/dna |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 4 |
| Total formula weight | 45775.65 |
| Authors | Moon, A.F.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Bebenek, K.,Pedersen, L.C. (deposition date: 2016-11-14, release date: 2017-07-05, Last modification date: 2023-10-04) |
| Primary citation | Moon, A.F.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Bebenek, K.,Pedersen, L.C. Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45:9138-9148, 2017 Cited by PubMed: 28911097DOI: 10.1093/nar/gkx527 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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