8DQS

The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023032

Summary for 8DQS

• Entry DOI: 10.2210/pdb8dqs/pdb
• Descriptor: Protein PA-X, MANGANESE (II) ION, 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-2-[4-(trifluoromethyl)phenyl]-3,6-dihydropyrimidine-4-carboxamide, ... (5 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein
• Biological source: Influenza A virus; More
• Total number of polymer chains: 1
• Total formula weight: 24361.46

Authors

Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W. (deposition date: 2022-07-19, release date: 2022-09-14, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W.; The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023032; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.45 Å)