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2GWS

Crystal Structure of human DNA Polymerase lambda with a G/G mismatch in the primer terminus

Summary for 2GWS
Entry DOI10.2210/pdb2gws/pdb
Descriptor5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... (10 entities in total)
Functional Keywordsdna polymerase lambda, family x, mismatch extension, mutagenesis, nhej, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus : Q9UGP5
Total number of polymer chains16
Total formula weight176302.77
Authors
Garcia-Diaz, M.,Picher, A.J.,Bebenek, K.,Pedersen, L.C.,Kunkel, T.A.,Blanco, L. (deposition date: 2006-05-05, release date: 2006-09-05, Last modification date: 2023-08-30)
Primary citationPicher, A.J.,Garcia-Diaz, M.,Bebenek, K.,Pedersen, L.C.,Kunkel, T.A.,Blanco, L.
Promiscuous mismatch extension by human DNA polymerase lambda.
Nucleic Acids Res., 34:3259-3266, 2006
Cited by
PubMed: 16807316
DOI: 10.1093/nar/gkl377
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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