2BCS
DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dcmp
Summary for 2BCS
Entry DOI | 10.2210/pdb2bcs/pdb |
Related | 2BCQ 2BCR 2BCU 2BCV |
Descriptor | 5'-D(*GP*CP*CP*G)-3', 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*CP*TP*AP*CP*TP*G)-3', ... (8 entities in total) |
Functional Keywords | misalignment, extrahelical, mutagenesis, mutation, deletion, streisinger, slippage, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UGP5 |
Total number of polymer chains | 4 |
Total formula weight | 44681.62 |
Authors | Garcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Pedersen, L.C.,Kunkel, T.A. (deposition date: 2005-10-19, release date: 2006-03-07, Last modification date: 2023-08-23) |
Primary citation | Garcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Pedersen, L.C.,Kunkel, T.A. Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124:331-342, 2006 Cited by PubMed: 16439207DOI: 10.1016/j.cell.2005.10.039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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