PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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6O7S	Nitrogenase MoFeP mutant S188A from Azotobacter vinelandii in the indigo carmine oxidized state 分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(6)-S(7) CLUSTER, ... 著者 Rutledge, H.L, Tezcan, F.A. 登録日 2019-03-08 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Redox-Dependent Metastability of the Nitrogenase P-Cluster. J.Am.Chem.Soc., 141, 2019
6O9H	Mouse ECD with Fab1 分子名称: Gastric inhibitory polypeptide receptor, Heavy chain, Light chain, ... 著者 Min, X, Wang, Z. 登録日 2019-03-13 公開日 2020-01-22 最終更新日 2020-04-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor. Mabs, 12, 2020
4WXG	Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine 分子名称: GLYCEROL, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, SODIUM ION, ... 著者 Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P. 登録日 2014-11-13 公開日 2015-02-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids. Angew.Chem.Int.Ed.Engl., 54, 2015
4WZI	Crystal structure of crosslink stabilized long-form PDE4B 分子名称: IODIDE ION, MAGNESIUM ION, SODIUM ION, ... 著者 Cedervall, P, Pandit, J. 登録日 2014-11-19 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4. Proc.Natl.Acad.Sci.USA, 112, 2015
3FO3	Structure of the Thioalkalivibrio nitratireducens cytochrome c nitrite reductase reduced by sodium dithionite (sulfite complex) 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Trofimov, A.A, Polyakov, K.M, Boyko, K.M, Slutsky, A, Tikhonova, T.V, Antipov, A.N, Zvyagilskaya, R.A, Popov, A.N, Lamzin, V.S, Bourenkov, G.P, Popov, V.O. 登録日 2008-12-27 公開日 2009-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structures of complexes of octahaem cytochrome c nitrite reductase from Thioalkalivibrio nitratireducens with sulfite and cyanide Acta Crystallogr.,Sect.D, 66, 2010
6MBN	LptB E163Q in complex with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Lipopolysaccharide export system ATP-binding protein LptB, ... 著者 Owens, T.W, Ruiz, N, Kahne, D. 登録日 2018-08-30 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.957 Å) 主引用文献 Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport. Mbio, 10, 2019
5B4V	Crystal structure of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate 分子名称: 3-hydroxybutyrate dehydrogenase, CHLORIDE ION, METHYLMALONIC ACID, ... 著者 Kanazawa, H, Tsunoda, M, Hoque, M.M, Suzuki, K, Yamamoto, T, Takenaka, A. 登録日 2016-04-19 公開日 2016-08-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase Acta Crystallogr.,Sect.F, 72, 2016
4WR8	Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180) 分子名称: 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ... 著者 Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. 登録日 2014-10-23 公開日 2015-03-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
3INM	Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase R132H mutant in complex with NADPH, ALPHA-KETOGLUTARATE and CALCIUM(2+) 分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, GLYCEROL, ... 著者 Fontano, E, Brown, R.S, Suto, R.K, Bhyravbhatla, B. 登録日 2009-08-12 公開日 2009-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature, 462, 2009
5APC	Hen Egg White Lysozyme illuminated with 0.4THz radiation 分子名称: LYSOZYME C, SODIUM ION 著者 Lundholm, I, Rodilla, H, Wahlgren, W.Y, Duelli, A, Bourenkov, G, Vukusic, J, Friedman, R, Stake, J, Schneider, T, Katona, G. 登録日 2015-09-15 公開日 2016-01-13 最終更新日 2018-03-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Terahertz Radiation Induces Non-Thermal Structural Changes Associated with Frohlich Condensation in a Protein Crystal Struct.Dyn., 2, 2015
6O53	Structure of HLA-A2:01 with peptide MM96 分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... 著者 Ying, G, Bitra, A, Zajonc, D.M. 登録日 2019-03-01 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Front Immunol, 10, 2019
6OSR	Crystal structure of Influenza hemagglutinin from strain A/Melbourne/1/1946(H1N1) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-05-02 公開日 2019-05-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site. Sci Rep, 13, 2023
6OUV	1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Deinococcus radiodurans with methylacetylphosphonate (MAP) bound 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, ... 著者 Chen, P.Y.-T, Drennan, C.L. 登録日 2019-05-05 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.937 Å) 主引用文献 X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate. J.Biol.Chem., 294, 2019
5BQS	S. Pneumoniae Fabh with small molecule inhibitor 4 分子名称: 1-{5-[2-chloro-5-(hydroxymethyl)phenyl]pyridin-2-yl}piperidine-4-carboxylic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 3, SODIUM ION 著者 Kazmirski, S.L, McKinney, D.C. 登録日 2015-05-29 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping. Acs Infect Dis., 2, 2016
6OKF	Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C16-crypto Acyl Carrier Protein, AcpP 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... 著者 Mindrebo, J.T, Kim, W.E, Bartholow, T.G, Chen, A, Davis, T.D, La Clair, J, Burkart, M.D, Noel, J.P. 登録日 2019-04-12 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Gating mechanism of elongating beta-ketoacyl-ACP synthases. Nat Commun, 11, 2020
3ISD	Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ... 著者 Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H. 登録日 2009-08-25 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". J.Biol.Chem., 284, 2009
4X5L	Crystal structure of Dscam1 Ig7 domain, isoform 9 分子名称: Down syndrome cell adhesion molecule, isoform AM, SODIUM ION 著者 Chen, Q, Yu, Y, Li, S.A, Cheng, L. 登録日 2014-12-05 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.374 Å) 主引用文献 Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
4YYF	The crystal structure of a glycosyl hydrolase of GH3 family member from [Mycobacterium smegmatis str. MC2 155 分子名称: ACETATE ION, Beta-N-acetylhexosaminidase, FORMIC ACID, ... 著者 Tan, K, Hatzos-Skintges, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2015-03-23 公開日 2015-04-08 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 The crystal structure of a glycosyl hydrolase of GH3 family member from [Mycobacterium smegmatis str. MC2 155 To Be Published
6OU1	Crystal Structure of the Computationally-derived 21-Variant of the Myocilin Olfactomedin Domain 分子名称: CALCIUM ION, GLYCEROL, Myocilin, ... 著者 Hill, S.E, Kwon, M.S, Lieberman, R.L. 登録日 2019-05-03 公開日 2019-07-03 最終更新日 2020-01-15 実験手法 X-RAY DIFFRACTION (1.878 Å) 主引用文献 Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations. J.Biol.Chem., 294, 2019
6OQQ	Legionella pneumophila SidJ/Saccharomyces cerevisiae calmodulin complex 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... 著者 Tomchick, D.R, Tagliabracci, V.S, Black, M, Osinski, A. 登録日 2019-04-28 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases. Science, 364, 2019
4XAE	Structure of Feruloyl-CoA 6-hydroxylase (F6H) from Arabidopsis thaliana 分子名称: Feruloyl CoA ortho-hydroxylase 1, SODIUM ION 著者 Zhou, D, Kandavelu, P, Zhang, H, Wang, B.C, Rose, J, Yan, Y. 登録日 2014-12-14 公開日 2015-06-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.769 Å) 主引用文献 Structural Insights into Substrate Specificity of Feruloyl-CoA 6'-Hydroxylase from Arabidopsis thaliana. Sci Rep, 5, 2015
4XEL	Crystal structure of Inorganic pyrophosphatase (PPase) from Pseudomonas aeruginosa 分子名称: CHLORIDE ION, DODECAETHYLENE GLYCOL, Inorganic pyrophosphatase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-12-24 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of Inorganic pyrophosphatase (PPase) from Pseudomonas aeruginosa to be published
6EUT	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (KSK67) 分子名称: (3~{R})-8-cyclopropyl-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-10-31 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
6EUZ	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK37) 分子名称: (3~{R})-8-methoxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, ... 著者 Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-10-31 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
4XNF	Tailspike protein double mutant D339A/E372Q of E. coli bacteriophage HK620 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... 著者 Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. 登録日 2015-01-15 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein. to be published

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