8G2Y
| Cryo-EM structure of ADGRF1 coupled to miniGs/q | 分子名称: | Adhesion G-protein-coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Jones, D, Rawson, S, Blacklow, S. | 登録日 | 2023-02-06 | 公開日 | 2023-05-10 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nat Commun, 14, 2023
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8FP5
| CDK2 liganded with ATP and Mg2+ | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cyclin-dependent kinase 2, ... | 著者 | Schonbrunn, E, Sun, L. | 登録日 | 2023-01-04 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun, 14, 2023
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8FOD
| Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in Apo state conformation II | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | 登録日 | 2022-12-30 | 公開日 | 2023-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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8FOE
| Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex bound to a template DNA | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | 登録日 | 2022-12-30 | 公開日 | 2023-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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8FOK
| Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the DNA elongation state | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | 登録日 | 2022-12-30 | 公開日 | 2023-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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6O1Q
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8FD1
| Crystal structure of photoactivated rhodopsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.25 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
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8FVJ
| Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5 | 分子名称: | Core-binding factor subunit beta, Cullin-5, Elongin-B, ... | 著者 | Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. | 登録日 | 2023-01-19 | 公開日 | 2023-09-06 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
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8FAC
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8FD0
| Crystal structure of bovine rod opsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
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8FCZ
| Crystal structure of ground-state rhodopsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
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8FVI
| Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5 | 分子名称: | Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ... | 著者 | Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. | 登録日 | 2023-01-19 | 公開日 | 2023-09-06 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
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8FR3
| E. coli EF-Tu in complex with KKL-55 | 分子名称: | 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M. | 登録日 | 2023-01-06 | 公開日 | 2023-09-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA. Mbio, 14, 2023
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3T5S
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8FX5
| Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline | 分子名称: | Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Vuckovic, Z, Mobbs, J.I, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. | 登録日 | 2023-01-23 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Xanomeline displays concomitant orthosteric and allosteric binding modes at the M 4 mAChR. Nat Commun, 14, 2023
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6H64
| Crystal structure of the CRD-SAT | 分子名称: | Galectin-3, SULFATE ION, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Charron, C, Kriznik, A, Yelehe-Okouma, M, Jouzeau, J.-Y, Reboul, P. | 登録日 | 2018-07-26 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | CRD SAT Generated by pCARGHO: A New Efficient Lectin-Based Affinity Tag Method for Safe, Simple, and Low-Cost Protein Purification. Biotechnol J, 14, 2019
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8FKM
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8FBQ
| Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 12b | 分子名称: | 1-[(3M)-3-{3-[2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethoxy]pyridin-2-yl}phenyl]piperazine, ACETATE ION, CHLORIDE ION, ... | 著者 | Fenwick, M.K, Staker, B.L, Lovell, S.W, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-11-29 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts. Nat Commun, 14, 2023
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8FWF
| Crystal structure of Apo form Fab235 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-21 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FXJ
| Crystal structure of Fab460 | 分子名称: | ACETATE ION, CHLORIDE ION, Fab460, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-24 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FYM
| Crystal structure of Fab235 in complex with MPER peptide | 分子名称: | ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-26 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FDO
| SARS-CoV-2 fusion peptide epitope scaffold FP15 bound to DH1058 | 分子名称: | DH1058 Heavy chain, DH1058 Light chain, FP15 | 著者 | Kapingidza, A.B, Marston, D.J, Wrapp, D, Winters, K, Azoitei, M.L. | 登録日 | 2022-12-04 | 公開日 | 2023-10-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. Nat Commun, 14, 2023
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8FZ2
| Crystal structure of Fab460 in complex with MPER peptide | 分子名称: | Fab460, H chain, L chain, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-27 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FK2
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8FFO
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