8FWF

Crystal structure of Apo form Fab235

Summary for 8FWF

• Entry DOI: 10.2210/pdb8fwf/pdb
• Descriptor: Fab235, light chain, Fab235, heavy chain, CHLORIDE ION, ... (9 entities in total)
• Functional Keywords: hiv, membrane proximal external region, mper, vaccine, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 50578.58

Authors

Tan, K.,Kim, M.,Reinherz, E.L. (deposition date: 2023-01-21, release date: 2023-10-11, Last modification date: 2024-03-06)

• Primary citation: Tan, K.,Chen, J.,Kaku, Y.,Wang, Y.,Donius, L.,Khan, R.A.,Li, X.,Richter, H.,Seaman, M.S.,Walz, T.,Hwang, W.,Reinherz, E.L.,Kim, M.; Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.; Nat Commun, 14:7218-7218, 2023; PubMed: 37940661; DOI: 10.1038/s41467-023-42097-6

Experimental method

X-RAY DIFFRACTION (1.94 Å)