8FR3

E. coli EF-Tu in complex with KKL-55

Summary for 8FR3

Entry DOI	10.2210/pdb8fr3/pdb
Descriptor	Elongation factor Tu, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	ef-tu, translation, antibiotic
Biological source	Escherichia coli K-12
Total number of polymer chains	2
Total formula weight	90027.93
Authors	Nguyen, H.A.,Kuzmishin Nagy, A.B.,Dunham, C.M. (deposition date: 2023-01-06, release date: 2023-09-20, Last modification date: 2023-11-29)
Primary citation	Marathe, N.,Nguyen, H.A.,Alumasa, J.N.,Kuzmishin Nagy, A.B.,Vazquez, M.,Dunham, C.M.,Keiler, K.C. Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA. Mbio, 14:e0146123-e0146123, 2023 Cited by PubMed: 37681945 DOI: 10.1128/mbio.01461-23 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation