8FD0
Crystal structure of bovine rod opsin in complex with a nanobody
Summary for 8FD0
Entry DOI | 10.2210/pdb8fd0/pdb |
Descriptor | Rhodopsin, Nanobody Nb2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | transmembrane protein, gpcr, nanobody, membrane protein |
Biological source | Lama glama (llama) More |
Total number of polymer chains | 4 |
Total formula weight | 108797.56 |
Authors | Salom, D.,Palczewski, K.,Kiser, P.D. (deposition date: 2022-12-01, release date: 2023-08-30, Last modification date: 2023-09-20) |
Primary citation | Wu, A.,Salom, D.,Hong, J.D.,Tworak, A.,Watanabe, K.,Pardon, E.,Steyaert, J.,Kandori, H.,Katayama, K.,Kiser, P.D.,Palczewski, K. Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14:5209-5209, 2023 Cited by PubMed: 37626045DOI: 10.1038/s41467-023-40911-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.71 Å) |
Structure validation
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