7F5W
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4N14
| Crystal structure of Cdc20 and apcin complex | 分子名称: | 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl [(1R)-2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate, Cell division cycle protein 20 homolog | 著者 | Luo, X, Tian, W, Yu, H. | 登録日 | 2013-10-03 | 公開日 | 2014-08-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. Nature, 514, 2014
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4M6L
| Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and 5,10-dideazatetrahydrofolic acid | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydrofolate reductase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, ... | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | 登録日 | 2013-08-09 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase. Nat.Struct.Mol.Biol., 20, 2013
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4D1T
| High resolution structure of native tVIM-7 from Pseudomonas aeruginosa | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | 登録日 | 2014-05-05 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother., 58, 2014
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4D1V
| A F218Y mutant of VIM-7 from Pseudomonas aeruginosa | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | 登録日 | 2014-05-05 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother., 58, 2014
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4FM9
| Human topoisomerase II alpha bound to DNA | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA topoisomerase 2-alpha, ... | 著者 | Wendorff, T.J, Schmidt, B.H, Heslop, P, Austin, C.A, Berger, J.M. | 登録日 | 2012-06-15 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | 主引用文献 | The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage. J.Mol.Biol., 424, 2012
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4G51
| Crystallographic analysis of the interaction of nitric oxide with hemoglobin from Trematomus bernacchii in the T quaternary structure (fully ligated state). | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, NITRIC OXIDE, ... | 著者 | Merlino, A, Balsamo, A, Pica, A, Mazzarella, L, Vergara, A. | 登録日 | 2012-07-17 | 公開日 | 2013-01-16 | 最終更新日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study. Acta Crystallogr.,Sect.D, 69, 2013
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4M6J
| Crystal structure of human dihydrofolate reductase (DHFR) bound to NADPH | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | 登録日 | 2013-08-09 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.201 Å) | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase. Nat.Struct.Mol.Biol., 20, 2013
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4D8D
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4DLG
| Ternary Structure of the large Fragment of Taq DNA polymerase | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA polymerase I, ... | 著者 | Marx, A, Diederichs, K, Obeid, S, Holzberger, B. | 登録日 | 2012-02-06 | 公開日 | 2012-11-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural insights into the potential of 4-fluoroproline to modulate biophysical properties of protein Chem Sci, 3, 2012
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4J8T
| Engineered Digoxigenin binder DIG10.2 | 分子名称: | DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.2 | 著者 | Stoddard, B.L, Doyle, L.A. | 登録日 | 2013-02-14 | 公開日 | 2013-06-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Computational design of ligand-binding proteins with high affinity and selectivity. Nature, 501, 2013
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4J9A
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4L49
| Structure of L358A mutant of P450cam bound to camphor | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.128 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4L4B
| Structure of L358A/K178G/D182N mutant of P450cam bound to camphor | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4L4G
| Structure of cyanide and camphor bound P450cam mutant L358P/K178G | 分子名称: | CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4L4A
| Structure of L358A/K178G mutant of P450cam bound to camphor | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4LWS
| EsxA : EsxB (SeMet) hetero-dimer from Thermomonospora curvata | 分子名称: | ACETATE ION, GLYCEROL, Uncharacterized protein | 著者 | Dovala, D.L, Cox, J.S, Stroud, R.M, Rosenberg, O.S. | 登録日 | 2013-07-28 | 公開日 | 2015-02-04 | 最終更新日 | 2016-09-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion. Cell(Cambridge,Mass.), 161, 2015
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4L4F
| Structure of cyanide and camphor bound P450cam mutant L358A/K178G/D182N | 分子名称: | CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.294 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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3QV7
| Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with ponceau S and acid blue 25. | 分子名称: | 3-hydroxy-4-[(E)-{2-sulfo-4-[(E)-(4-sulfophenyl)diazenyl]phenyl}diazenyl]naphthalene-2,7-disulfonic acid, 9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonic acid, POTASSIUM ION, ... | 著者 | Morgan, H.P, Auld, D.S, McNae, I.W, Nowicki, M.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2011-02-25 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. J.Biol.Chem., 286, 2011
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3QV6
| Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with acid blue 80. | 分子名称: | 3-({4-[(2,4-dimethyl-5-sulfophenyl)amino]-9,10-dioxo-9,10-dihydroanthracen-1-yl}amino)-2,4,6-trimethylbenzenesulfonic acid, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Morgan, H.P, Auld, D.S, McNae, I.W, Nowicki, M.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2011-02-25 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. J.Biol.Chem., 286, 2011
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3QV8
| Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with benzothiazole-2,5-disulfonic acid. | 分子名称: | 1,3-benzothiazole-2,5-disulfonic acid, PHOSPHATE ION, Pyruvate kinase | 著者 | Morgan, H.P, Auld, D.S, McNae, I.W, Nowicki, M.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2011-02-25 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. J.Biol.Chem., 286, 2011
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4LEO
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4L4C
| Structure of L358P/K178G mutant of P450cam bound to camphor | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4L4D
| Structure of cyanide and camphor bound P450cam mutant L358A | 分子名称: | CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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7F7E
| SARS-CoV-2 S protein RBD in complex with A5-10 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A5-10 Fab, Light chain of A5-10 Fab, ... | 著者 | Dou, Y, Wang, X, Wang, K, Liu, P, Lu, B. | 登録日 | 2021-06-29 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants. Emerg Microbes Infect, 11, 2022
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