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7E5A
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interferon-inducible anti-viral protein R356A
分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ...
著者Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
登録日2021-02-18
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
6G19
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CryoEM structure of the MDA5-dsRNA filament with 74-degree helical twist
分子名称: Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
著者Yu, Q, Qu, K, Modis, Y.
登録日2018-03-20
公開日2018-11-21
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1X
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CryoEM structure of the MDA5-dsRNA filament with 91-degree helical twist
分子名称: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
著者Yu, Q, Qu, K, Modis, Y.
登録日2018-03-22
公開日2018-11-21
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1S
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CryoEM structure of the MDA5-dsRNA filament with 87-degree helical twist
分子名称: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
著者Yu, Q, Qu, K, Modis, Y.
登録日2018-03-21
公開日2018-11-21
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
4N71
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X-Ray Crystal Structure of 2-amino-1-hydroxyethylphosphonate-bound PhnZ
分子名称: FE (III) ION, Predicted HD phosphohydrolase PhnZ, [(1R)-2-amino-1-hydroxyethyl]phosphonic acid
著者Woersdoerfer, B, Lingaraju, M, Yennawar, N, Boal, A.K, Krebs, C, Bollinger Jr, J.M, Pandelia, M.-E.
登録日2013-10-14
公開日2013-11-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases.
Proc.Natl.Acad.Sci.USA, 110, 2013
6DHI
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BU of 6dhi by Molmil
Butelase 1: Auto-Catalytic Cleavage as an Evolutionary Constraint for Macrocyclizing Endopeptidases
分子名称: Asparaginyl endopeptidase
著者Bond, C.S, Haywood, J.
登録日2018-05-20
公開日2018-08-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The macrocyclizing protease butelase 1 remains autocatalytic and reveals the structural basis for ligase activity.
Plant J., 98, 2019
1EKU
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BU of 1eku by Molmil
CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA
分子名称: Interferon gamma, SULFATE ION
著者Landar, A, Curry, B, Parker, M.H, DiGiacomo, R, Indelicato, S.R, Walter, M.R.
登録日2000-03-09
公開日2000-09-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.
J.Mol.Biol., 299, 2000
3BU8
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Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex
分子名称: TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2
著者Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M.
登録日2008-01-02
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
4L5Q
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Crystal structure of p202 HIN1
分子名称: Interferon-activable protein 202
著者Yin, Q, Tian, Y, Wu, H.
登録日2013-06-11
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation.
Cell Rep, 4, 2013
4L5T
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Crystal structure of the tetrameric p202 HIN2
分子名称: Interferon-activable protein 202
著者Yin, Q, Tian, Y, Wu, H.
登録日2013-06-11
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.405 Å)
主引用文献Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation.
Cell Rep, 4, 2013
6C6K
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BU of 6c6k by Molmil
Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex
分子名称: Interferon-induced protein with tetratricopeptide repeats 1, Interferon-induced protein with tetratricopeptide repeats 3, MAGNESIUM ION, ...
著者Amarasinghe, G.K, Leung, D.W, Johnson, B, Xu, W.
登録日2018-01-18
公開日2018-04-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability.
Immunity, 48, 2018
4WHJ
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Myxovirus Resistance Protein 2 (MxB)
分子名称: Interferon-induced GTP-binding protein Mx2
著者Xiong, Y, Fribourgh, J.L, Nguyen, H.C.
登録日2014-09-22
公開日2014-10-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Insight into HIV-1 Restriction by MxB.
Cell Host Microbe, 16, 2014
7K3R
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BU of 7k3r by Molmil
Cryo-EM structure of AIM2-PYD filament
分子名称: Interferon-inducible protein AIM2
著者Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
登録日2020-09-12
公開日2021-05-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome.
Nat Commun, 12, 2021
8IZN
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Structural study of Interferon-induced, double-stranded RNA-activated protein kinase (PKR) and Non-structural protein 1 (NS1) complex
分子名称: Interferon-induced, double-stranded RNA-activated protein kinase, Non-structural protein 1
著者Han, C.W, Kim, H.J.
登録日2023-04-07
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (6.67 Å)
主引用文献Structure of PKR and NS1 complex
To Be Published
8H6Q
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BU of 8h6q by Molmil
Class I sesquiterpene synthase BCBOT2 (apo)
分子名称: Presilphiperfolan-8-beta-ol synthase
著者Lou, T.T, Ma, M.
登録日2022-10-18
公開日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis.
J.Am.Chem.Soc., 2023
5OEN
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BU of 5oen by Molmil
Crystal Structure of STAT2 in complex with IRF9
分子名称: Interferon regulatory factor 9, Signal transducer and activator of transcription
著者Rengachari, S, Panne, D.
登録日2017-07-09
公開日2018-01-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.919 Å)
主引用文献Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7X45
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Grass carp interferon gamma related
分子名称: Interferon gamma
著者Wang, J, Zou, J, Zhu, X.
登録日2022-03-02
公開日2022-09-14
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Novel Dimeric Architecture of an IFN-gamma-Related Cytokine Provides Insights into Subfunctionalization of Type II IFNs in Teleost Fish.
J Immunol., 209, 2022
1AHM
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DER F 2, THE MAJOR MITE ALLERGEN FROM DERMATOPHAGOIDES FARINAE, NMR, 10 STRUCTURES
分子名称: DER F 2
著者Ichikawa, S, Hatanaka, H, Yuuki, T, Iwamoto, N, Ogura, K, Okumura, Y, Inagaki, F.
登録日1997-04-07
公開日1998-04-08
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of Der f 2, the major mite allergen for atopic diseases.
J.Biol.Chem., 273, 1998
1AHK
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DER F 2, THE MAJOR MITE ALLERGEN FROM DERMATOPHAGOIDES FARINAE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: DER F 2
著者Ichikawa, S, Hatanaka, H, Yuuki, T, Iwamoto, N, Ogura, K, Okumura, Y, Inagaki, F.
登録日1997-04-07
公開日1998-04-08
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of Der f 2, the major mite allergen for atopic diseases.
J.Biol.Chem., 273, 1998
7WKH
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BU of 7wkh by Molmil
the grass carp IFNa
分子名称: Interferon
著者Zou, J, WANG, J, Wang, Z.
登録日2022-01-09
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish.
Front Immunol, 13, 2022
7DNJ
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BU of 7dnj by Molmil
K63-polyUb MDA5CARDs complex
分子名称: Interferon-induced helicase C domain-containing protein 1, Ubiquitin
著者Song, B, Chen, Y, Luo, D.H, Zheng, J.
登録日2020-12-09
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
7DNI
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BU of 7dni by Molmil
MDA5 CARDs-MAVS CARD polyUb complex
分子名称: Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin
著者Song, B, Chen, Y, Luo, D.H, Zheng, J.
登録日2020-12-09
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
8JKS
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T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAGA motif
分子名称: GAGA-Forward, GAGA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKL
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IRF4 DNA-binding domain bound to an DNA containing GATA motif
分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKQ
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T95R mutant IRF4 DNA-binding domain bound to an DNA containing GACA motif
分子名称: GACA-Forward, GACA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023

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