3BU8

Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex

Summary for 3BU8

Entry DOI	10.2210/pdb3bu8/pdb
Related	3BQO 3BUA
Descriptor	Telomeric repeat-binding factor 2, TERF1-interacting nuclear factor 2 (3 entities in total)
Functional Keywords	trf2 trfh domain trf2 dimerization domain tin2 peptide, alternative splicing, cell cycle, chromosomal protein, dna-binding, nucleus, phosphoprotein, telomere, dna binding protein
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q15554 Nucleus. Isoform 1: Nucleus matrix: Q9BSI4
Total number of polymer chains	4
Total formula weight	58269.28
Authors	Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M. (deposition date: 2008-01-02, release date: 2008-02-19, Last modification date: 2023-08-30)
Primary citation	Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M. A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319:1092-1096, 2008 Cited by PubMed: 18202258 DOI: 10.1126/science.1151804 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation