3BU8
Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000723 | biological_process | telomere maintenance |
| A | 0000781 | cellular_component | chromosome, telomeric region |
| A | 0005634 | cellular_component | nucleus |
| A | 0031848 | biological_process | protection from non-homologous end joining at telomere |
| A | 0042162 | molecular_function | telomeric DNA binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0000723 | biological_process | telomere maintenance |
| B | 0000781 | cellular_component | chromosome, telomeric region |
| B | 0005634 | cellular_component | nucleus |
| B | 0031848 | biological_process | protection from non-homologous end joining at telomere |
| B | 0042162 | molecular_function | telomeric DNA binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by ATM","evidences":[{"source":"PubMed","id":"16223874","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
