1EKU
CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA
Summary for 1EKU
Entry DOI | 10.2210/pdb1eku/pdb |
Descriptor | Interferon gamma, SULFATE ION (3 entities in total) |
Functional Keywords | cytokine, protein engineering, interferon, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P01579 |
Total number of polymer chains | 2 |
Total formula weight | 63019.25 |
Authors | Landar, A.,Curry, B.,Parker, M.H.,DiGiacomo, R.,Indelicato, S.R.,Walter, M.R. (deposition date: 2000-03-09, release date: 2000-09-01, Last modification date: 2024-02-07) |
Primary citation | Landar, A.,Curry, B.,Parker, M.H.,DiGiacomo, R.,Indelicato, S.R.,Nagabhushan, T.L.,Rizzi, G.,Walter, M.R. Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma. J.Mol.Biol., 299:169-179, 2000 Cited by PubMed: 10860730DOI: 10.1006/jmbi.2000.3734 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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