1EKU
CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Interferon gamma | polymer | 265 | 31173.4 | 2 | UniProt (P01579) Pfam (PF00714) In PDB | Homo sapiens (Human) | IFN-gamma,Immune interferon |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
3 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 121 (UniProt: P01579)
A, B: 123 - 258 (UniProt: P01579)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Asp 111 | His 134 | engineered mutation |
Phe 120 | Leu 143 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 122 | - | linker |
Glu 122 | - | linker |
Glu 122 | - | linker |
Gln 122 | - | linker |
Gln 122 | - | linker |
Glu 122 | - | linker |
Gly 122 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 62346.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 672.4 | |
All* | Total formula weight | 63019.2 |