6HYT
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![BU of 6hyt by Molmil](/molmil-images/mine/6hyt) | Crystal structure of DHX8 helicase domain bound to ADP at 2.3 Angstrom | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Felisberto-Rodrigues, C, Thomas, J.C, McAndrew, P.C, Le Bihan, Y.V, Burke, R, Workman, P, van Montfort, R.L.M. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. Biochem.J., 476, 2019
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6HYU
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![BU of 6hyu by Molmil](/molmil-images/mine/6hyu) | Crystal structure of DHX8 helicase bound to single stranded poly-adenine RNA | 分子名称: | 1,2-ETHANEDIOL, ATP-dependent RNA helicase DHX8, RNA (5'-R(*A*AP*A)-3'), ... | 著者 | Felisberto-Rodrigues, C, Thomas, J.C, McAndrew, P.C, Le Bihan, Y.V, Burke, R, Workman, P, van Montfort, R.L.M. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. Biochem.J., 476, 2019
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6I3O
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![BU of 6i3o by Molmil](/molmil-images/mine/6i3o) | |
6I3P
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![BU of 6i3p by Molmil](/molmil-images/mine/6i3p) | |
6QDV
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![BU of 6qdv by Molmil](/molmil-images/mine/6qdv) | Human post-catalytic P complex spliceosome | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. | 登録日 | 2019-01-03 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science, 363, 2019
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6QID
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![BU of 6qid by Molmil](/molmil-images/mine/6qid) | Crystal structure of DEAH-box ATPase Prp43-S387A | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Hamann, F, Ficner, R, Enders, M. | 登録日 | 2019-01-18 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | 主引用文献 | Structural basis for RNA translocation by DEAH-box ATPases. Nucleic Acids Res., 47, 2019
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6QIE
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![BU of 6qie by Molmil](/molmil-images/mine/6qie) | Crystal structure of DEAH-box ATPase Prp43-S387G | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Hamann, F, Ficner, R, Enders, M. | 登録日 | 2019-01-18 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for RNA translocation by DEAH-box ATPases. Nucleic Acids Res., 47, 2019
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6QIC
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6O16
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![BU of 6o16 by Molmil](/molmil-images/mine/6o16) | Crystal structure of murine DHX37 in complex with RNA | 分子名称: | DEAH (Asp-Glu-Ala-His) box polypeptide 37, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') | 著者 | Boneberg, F, Brandmann, T, Kobel, L, van den Heuvel, J, Bargsten, K, Bammert, L, Kutay, U, Jinek, M. | 登録日 | 2019-02-18 | 公開日 | 2019-04-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.875 Å) | 主引用文献 | Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis. Rna, 25, 2019
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6QV3
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![BU of 6qv3 by Molmil](/molmil-images/mine/6qv3) | Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum bound to ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | 著者 | Absmeier, E, Santos, K.F, Wahl, M.C. | 登録日 | 2019-03-01 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 2020
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6QV4
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![BU of 6qv4 by Molmil](/molmil-images/mine/6qv4) | Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum bound to ATP-gamma-S | 分子名称: | ACETATE ION, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Absmeier, E, Santos, K.F, Wahl, M.C. | 登録日 | 2019-03-01 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 2020
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6O5F
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6QW6
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![BU of 6qw6 by Molmil](/molmil-images/mine/6qw6) | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | 登録日 | 2019-03-05 | 公開日 | 2019-04-17 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
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6QWS
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6QX9
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![BU of 6qx9 by Molmil](/molmil-images/mine/6qx9) | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | 登録日 | 2019-03-07 | 公開日 | 2019-04-17 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
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6RM9
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![BU of 6rm9 by Molmil](/molmil-images/mine/6rm9) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2019-05-06 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RMC
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![BU of 6rmc by Molmil](/molmil-images/mine/6rmc) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | 著者 | Hamann, F, Neumann, P, Schmitt, A, Ficner, R. | 登録日 | 2019-05-06 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RMA
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![BU of 6rma by Molmil](/molmil-images/mine/6rma) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2019-05-06 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RM8
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![BU of 6rm8 by Molmil](/molmil-images/mine/6rm8) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | 著者 | Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2019-05-06 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RMB
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![BU of 6rmb by Molmil](/molmil-images/mine/6rmb) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | 著者 | Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2019-05-06 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RO1
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![BU of 6ro1 by Molmil](/molmil-images/mine/6ro1) | X-ray crystal structure of the MTR4 NVL complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | 著者 | Lingaraju, M, Langer, L.M, Basquin, J, Falk, S, Conti, E. | 登録日 | 2019-05-10 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs. Nat Commun, 10, 2019
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6S8Q
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6S8O
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![BU of 6s8o by Molmil](/molmil-images/mine/6s8o) | Human Brr2 Helicase Region M641C/A1582C | 分子名称: | U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Vester, K, Santos, K.F, Wahl, M.C. | 登録日 | 2019-07-10 | 公開日 | 2020-01-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.172 Å) | 主引用文献 | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295, 2020
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6S9I
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6SH7
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![BU of 6sh7 by Molmil](/molmil-images/mine/6sh7) | |