6HYT
Crystal structure of DHX8 helicase domain bound to ADP at 2.3 Angstrom
Summary for 6HYT
Entry DOI | 10.2210/pdb6hyt/pdb |
Descriptor | ATP-dependent RNA helicase DHX8, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (8 entities in total) |
Functional Keywords | helicase, splicing, rna, rna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 311383.25 |
Authors | Felisberto-Rodrigues, C.,Thomas, J.C.,McAndrew, P.C.,Le Bihan, Y.V.,Burke, R.,Workman, P.,van Montfort, R.L.M. (deposition date: 2018-10-22, release date: 2019-08-28, Last modification date: 2024-05-15) |
Primary citation | Felisberto-Rodrigues, C.,Thomas, J.C.,McAndrew, C.,Le Bihan, Y.V.,Burke, R.,Workman, P.,van Montfort, R.L.M. Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. Biochem.J., 476:2521-2543, 2019 Cited by PubMed: 31409651DOI: 10.1042/BCJ20190383 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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