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6HYT

Crystal structure of DHX8 helicase domain bound to ADP at 2.3 Angstrom

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
ATP-dependent RNA helicase DHX8polymer67376822.64UniProt (Q14562)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF04408)
Pfam (PF21010)
Pfam (PF07717)
Homo sapiens (Human)DEAH box protein 8,RNA helicase HRH1
2CA, E, LA, O
(C, A, D, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.24Chemie (ADP)
3DA, F, MA, P
(C, A, D, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4EA, FA, G, H, I...
(C, A, D, B)
1,2-ETHANEDIOLnon-polymer62.110Chemie (EDO)
5GA, HA, IA, J, JA...
(C, A, D, B)
DIMETHYL SULFOXIDEnon-polymer78.118Chemie (DMS)
6AA, M
(B, A)
ACETATE IONnon-polymer59.02Chemie (ACT)
7BA, KA, N, TA
(B, C, A, D)
CHLORIDE IONnon-polymer35.54Chemie (CL)
8UA, VA, WA, XA
(A, B, C, D)
waterwater18.0606Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight307290.2
Non-Polymers*Number of molecules42
Total formula weight4093.0
All*Total formula weight311383.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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