6O16

Crystal structure of murine DHX37 in complex with RNA

Summary for 6O16

DescriptorDEAH (Asp-Glu-Ala-His) box polypeptide 37, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') (2 entities in total)
Functional Keywordsrna helicase, ribosome biogenesis, rna-dependent atpase, hydrolase-rna complex, hydrolase/rna
Biological sourceMus musculus (Mouse)
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Total number of polymer chains4
Total molecular weight223464.35
Authors
Boneberg, F.,Brandmann, T.,Kobel, L.,van den Heuvel, J.,Bargsten, K.,Bammert, L.,Kutay, U.,Jinek, M. (deposition date: 2019-02-18, release date: 2019-04-17, Last modification date: 2019-05-29)
Primary citation
Boneberg, F.M.,Brandmann, T.,Kobel, L.,van den Heuvel, J.,Bargsten, K.,Bammert, L.,Kutay, U.,Jinek, M.
Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.
Rna, 25:685-701, 2019
PubMed: 30910870 (PDB entries with the same primary citation)
DOI: 10.1261/rna.069609.118
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.875 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.293160 5.4% 6.9% 0.32MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution