6S9I
Human Brr2 Helicase Region D534C/N1866C in complex with C-tail deleted Jab1
Summary for 6S9I
Entry DOI | 10.2210/pdb6s9i/pdb |
Descriptor | U5 small nuclear ribonucleoprotein 200 kDa helicase, Pre-mRNA-processing-splicing factor 8 (3 entities in total) |
Functional Keywords | rnp remodeling, pre-mrna splicing, spliceosome catalytic activation, dexd/h-box rna helicase, rna and atp binding, nucleus, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 229776.96 |
Authors | Vester, K.,Santos, K.F.,Wahl, M.C. (deposition date: 2019-07-13, release date: 2020-01-22, Last modification date: 2020-02-26) |
Primary citation | Vester, K.,Santos, K.F.,Kuropka, B.,Weise, C.,Wahl, M.C. The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295:2097-2112, 2020 Cited by PubMed: 31914407DOI: 10.1074/jbc.RA119.010964 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.598 Å) |
Structure validation
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