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6S9I

Human Brr2 Helicase Region D534C/N1866C in complex with C-tail deleted Jab1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
U5 small nuclear ribonucleoprotein 200 kDa helicasepolymer1747199643.71UniProt (O75643)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF02889)
Homo sapiens (Human)Activating signal cointegrator 1 complex subunit 3-like 1,BRR2 homolog,U5 snRNP-specific 200 kDa protein,U5-200KD
2B
(J)
Pre-mRNA-processing-splicing factor 8polymer26330133.21UniProt (Q6P2Q9)
Pfam (PF01398)
Pfam (PF08084)
Homo sapiens (Human)220 kDa U5 snRNP-specific protein,PRP8 homolog,Splicing factor Prp8,p220
3C, D
(B, J)
waterwater18.0102Chemie (HOH)
Sequence modifications
B: 394 - 2136 (UniProt: O75643)
PDBExternal DatabaseDetails
Gly 390-expression tag
Ala 391-expression tag
Glu 392-expression tag
Phe 393-expression tag
Cys 534Asp 534engineered mutation
Cys 1866Asn 1866engineered mutation
J: 2064 - 2320 (UniProt: Q6P2Q9)
PDBExternal DatabaseDetails
Gly 2058-expression tag
Pro 2059-expression tag
Leu 2060-expression tag
Gly 2061-expression tag
Ser 2062-expression tag
Met 2063-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight229777.0
All*Total formula weight229777.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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