PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

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3C52	Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with phosphoglycolohydroxamic acid, a competitive inhibitor 分子名称: CALCIUM ION, Fructose-bisphosphate aldolase, PHOSPHOGLYCOLOHYDROXAMIC ACID, ... 著者 Coincon, M, Sygusch, J. 登録日 2008-01-30 公開日 2008-08-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics. Chemistry, 14, 2008
7BOD	Bacterial 30S ribosomal subunit assembly complex state M (body domain) 分子名称: 16S rRNA (body domain of 30S subunit), 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R. 登録日 2021-01-25 公開日 2021-07-07 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
7BOF	Bacterial 30S ribosomal subunit assembly complex state I (body domain) 分子名称: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2021-01-25 公開日 2021-07-07 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
8GKV	Crystal structure of anti-adaptor IraP that regulates RpoS proteolysis 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Shaw, G.X, Gan, J, Suburaman, P, Battesti, A, Zhou, Y.N, Wickner, S, Gottesman, S, Ji, X. 登録日 2023-03-20 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Structural and functional study of anti-adaptor IraP-mediated regulation of RpoS proteolysis to be published
8DKN	PPARg bound to T0070907 and Co-R peptide 分子名称: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Nuclear receptor corepressor 1 peptide, ... 著者 Larsen, N.A, Tsai, J. 登録日 2022-07-05 公開日 2022-09-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPAR gamma by inverse agonists. J.Biol.Chem., 298, 2022
8DSZ	PPARg bound to partial agonist H3B-487 分子名称: (2R)-2-{5-[(5-{[(1R)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}propanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Larsen, N.A. 登録日 2022-07-24 公開日 2022-09-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPAR gamma by inverse agonists. J.Biol.Chem., 298, 2022
8DKV	PPARg bound to JTP-426467 and Co-R peptide 分子名称: 2-chloro-N-[4-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-5-nitrobenzamide, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Nuclear receptor corepressor 1, ... 著者 Larsen, N.A. 登録日 2022-07-06 公開日 2022-09-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPAR gamma by inverse agonists. J.Biol.Chem., 298, 2022
5E7V	Potent Vitamin D Receptor Agonist 分子名称: 1-ALPHA-HYDROXY-27-NOR-25-O-CARBONYL-VITAMIN D3, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Otero, R, Seoane, S, Sigueiro, R, Belorusova, A.Y, Maestro, M.A, Perez-Fernandez, R, Rochel, N, Mourino, A. 登録日 2015-10-13 公開日 2015-11-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Carborane-based design of a potent vitamin D receptor agonist. Chem Sci, 7, 2016
3B91	Minimally Hinged Hairpin Ribozyme Incorporates Ade38(2AP) and 2',5'-Phosphodiester Linkage Mutations at the Active Site 分子名称: 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... 著者 MacElrevey, C, Krucinska, J, Wedekind, J.E. 登録日 2007-11-02 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
5GT4	Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol 分子名称: 4-{[(1R,2S,3R,5Z,7E,14beta,17alpha)-1,3,25-trihydroxy-9,10-secocholesta-5,7,10-trien-2-yl]oxy}butanenitrile, Vitamin D3 receptor 著者 Takimoto-Kamimura, M. 登録日 2016-08-18 公開日 2016-11-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol To Be Published
3BAL	Crystal Structure of an Acetylacetone Dioxygenase from Acinetobacter johnsonii 分子名称: Acetylacetone-cleaving enzyme, ZINC ION 著者 Stranzl, G.R, Wagner, U.G, Straganz, G, Steiner, W, Kratky, C. 登録日 2007-11-08 公開日 2007-11-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of an Acetylacetone Dioxygenase from Acinetobacter johnsonii To be Published
8PJJ	Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7UUC RNA 著者 Jagtap, P.K.A, Hennig, J. 登録日 2023-06-23 公開日 2023-11-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
5GTN	Human PPARgamma ligand binding dmain complexed with R35 分子名称: 2-[4-[5-[(1~{R})-1-[(3,5-dimethoxyphenyl)carbamoyl-(phenylmethyl)carbamoyl]oxypropyl]-1,2-oxazol-3-yl]phenoxy]-2-methyl-propanoic acid, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma 著者 Jang, J.Y, Suh, S.W. 登録日 2016-08-22 公開日 2017-07-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis for differential activities of enantiomeric PPAR gamma agonists: Binding of S35 to the alternate site. Biochim. Biophys. Acta, 1865, 2017
3B58	Minimally Junctioned Hairpin Ribozyme Incorporates A38G Mutation and a 2',5'-Phosphodiester Linkage at the Active Site 分子名称: 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... 著者 MacElrevey, C, Krucinska, J, Wedekind, J.E. 登録日 2007-10-25 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
8H69	Cryo-EM structure of influenza RNA polymerase 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ... 著者 Li, H, Wu, Y, Liang, H, Liu, Y. 登録日 2022-10-16 公開日 2023-06-28 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles. Nat.Struct.Mol.Biol., 30, 2023
3BA7	Crystal structure of L26N/D28A mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2007-11-07 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
8GWO	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: Helicase, Non-structural protein 7, Non-structural protein 8, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-11-30 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWG	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWI	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
3B5S	Minimally Hinged Hairpin Ribozyme Incorporates A38DAP Mutation and 2'-O-methyl Modification at the Active Site 分子名称: 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... 著者 MacElrevey, C, Krucinska, J, Wedekind, J.E. 登録日 2007-10-26 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
8GWB	SARS-CoV-2 E-RTC complex with RNA-nsp9 分子名称: Helicase, MANGANESE (II) ION, Non-structural protein 7, ... 著者 Yan, L.M, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-16 公開日 2022-12-07 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWN	A mechanism for SARS-CoV-2 RNA capping and its inhibitor of AT-527 分子名称: Helicase, Non-structural protein 7, Non-structural protein 8, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
6FT6	Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors 分子名称: 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... 著者 Schuller, J.M, Falk, S, Conti, E. 登録日 2018-02-20 公開日 2018-03-28 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
4O2H	Crystal structure of BCAM1869 protein (RsaM homolog) from Burkholderia cenocepacia 分子名称: protein BCAM1869 著者 Michalska, K, Chhor, G, Clancy, S, Winans, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2013-12-17 公開日 2014-01-22 最終更新日 2014-10-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 RsaM: a transcriptional regulator of Burkholderia spp. with novel fold. Febs J., 281, 2014
4NH1	Crystal structure of a heterotetrameric CK2 holoenzyme complex carrying the Andante-mutation in CK2beta and consistent with proposed models of autoinhibition and trans-autophosphorylation 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, GLYCEROL, ... 著者 Schnitzler, A, Issinger, O.-G, Niefind, K. 登録日 2013-11-04 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 The Protein Kinase CK2(Andante) Holoenzyme Structure Supports Proposed Models of Autoregulation and Trans-Autophosphorylation J.Mol.Biol., 426, 2014

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