5GT4

Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol

Replaces:  4PA2

Summary for 5GT4

• Entry DOI: 10.2210/pdb5gt4/pdb
• Descriptor: Vitamin D3 receptor, 4-{[(1R,2S,3R,5Z,7E,14beta,17alpha)-1,3,25-trihydroxy-9,10-secocholesta-5,7,10-trien-2-yl]oxy}butanenitrile (3 entities in total)
• Functional Keywords: nuclear hormone receptor full agonist ligand complex, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29448.14

Authors

Takimoto-Kamimura, M. (deposition date: 2016-08-18, release date: 2016-11-09, Last modification date: 2023-11-08)

• Primary citation: Takimoto-Kamimura, M.; Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.83 Å)