5GT4

Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol

Replaces:  4PA2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Vitamin D3 receptor	polymer	255	28948.4	1	UniProt (P11473) Pfam (PF00104)	Homo sapiens (Human)	VDR,1,25-dihydroxyvitamin D3 receptor,Nuclear receptor subfamily 1 group I member 1
2	B (A)	4-{[(1R,2S,3R,5Z,7E,14beta,17alpha)-1,3,25-trihydroxy-9,10-secocholesta-5,7,10-trien-2-yl]oxy}butanenitrile	non-polymer		499.7	1	Chemie (2KB)
3	C (A)	water	water		18.0	71	Chemie (HOH)

Sequence modifications

A: 118 - 164 (UniProt: P11473)
A: 216 - 423 (UniProt: P11473)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28948.4
Non-Polymers*	Number of molecules	1
	Total formula weight	499.7
All*	Total formula weight	29448.1

*Water molecules are not included.