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5GT4

Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol

Replaces:  4PA2
Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues15
Detailsbinding site for residue 2KB A 501
ChainResidue
ATYR143
ASER275
ASER278
ATRP286
AHIS305
AHIS397
AHOH658
AASP144
ATYR147
APHE150
ALEU227
ALEU233
AVAL234
ASER237
AARG274

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsBINDING: BINDING => ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:11344298
ChainResidueDetails
AHIS305
AHIS397
ATYR143
ALEU227
AILE271

219869

PDB entries from 2024-05-15

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