5E7V

Potent Vitamin D Receptor Agonist

Summary for 5E7V

• Entry DOI: 10.2210/pdb5e7v/pdb
• Descriptor: Vitamin D3 receptor A, Nuclear receptor coactivator 1, 1-ALPHA-HYDROXY-27-NOR-25-O-CARBONYL-VITAMIN D3, ... (4 entities in total)
• Functional Keywords: transcription, vitamin d nuclear receptor, vdr, ligand binding domain
• Biological source: Danio rerio (Zebrafish); More
• Cellular location: Nucleus: Q9PTN2
• Total number of polymer chains: 2
• Total formula weight: 36182.30

Authors

Otero, R.,Seoane, S.,Sigueiro, R.,Belorusova, A.Y.,Maestro, M.A.,Perez-Fernandez, R.,Rochel, N.,Mourino, A. (deposition date: 2015-10-13, release date: 2015-11-25, Last modification date: 2024-01-10)

• Primary citation: Otero, R.,Seoane, S.,Sigueiro, R.,Belorusova, A.Y.,Maestro, M.A.,Perez-Fernandez, R.,Rochel, N.,Mourino, A.; Carborane-based design of a potent vitamin D receptor agonist.; Chem Sci, 7:1033-1037, 2016; PubMed: 28808527; DOI: 10.1039/c5sc03084f

Experimental method

X-RAY DIFFRACTION (2.4 Å)