PDB: 98546 件ウェブページステータス検索Chemie searchBIRD

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8QKB	Crystal structure of human cathepsin L in complex with the vinyl sulfone inhibitor K777 分子名称: 1,2-ETHANEDIOL, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... 著者 Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. 登録日 2023-09-14 公開日 2023-09-27 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
4EE6	Crystal Structure of the Novel Phenazine Prenyltransferase EpzP (methylated) 分子名称: CHLORIDE ION, MAGNESIUM ION, Prenyltransferase, ... 著者 Zocher, G, Stehle, T. 登録日 2012-03-28 公開日 2012-11-14 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase. Plos One, 7, 2012
4LHV	Crystal structure of Rab8 in its inactive GDP-bound form 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-8A 著者 Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. 登録日 2013-07-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB. J.Biol.Chem., 288, 2013
4LHZ	Crystal structure of GTP-bound Rab8:Rabin8 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Rab-3A-interacting protein, Ras-related protein Rab-8A 著者 Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. 登録日 2013-07-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB. J.Biol.Chem., 288, 2013
4LHY	Crystal structure of GDP-bound Rab8:Rabin8 分子名称: GUANOSINE-5'-DIPHOSPHATE, Rab-3A-interacting protein, Ras-related protein Rab-8A, ... 著者 Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. 登録日 2013-07-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB. J.Biol.Chem., 288, 2013
5XDN	Crystal structure of human voltage-dependent anion channel 1 (hVDAC1) in P22121 space group 分子名称: DECANE, DODECANE, HEXANE, ... 著者 Hosaka, T, Kimura-Someya, T, Shirouzu, M. 登録日 2017-03-28 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Crystal structural characterization reveals novel oligomeric interactions of human voltage-dependent anion channel 1 Protein Sci., 26, 2017
4EE7	Crystal Structure of the Novel Phenazine Prenyltransferase EpzP in complex with S-thiolodiphosphate (methylated) 分子名称: CHLORIDE ION, Prenyltransferase, SULFATE ION, ... 著者 Zocher, G, Stehle, T. 登録日 2012-03-28 公開日 2012-11-14 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase. Plos One, 7, 2012
4EE8	Crystal structure of the Novel Phenazine Prenyltransferase EpzP (wildtype) 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, CHLORIDE ION, ... 著者 Zocher, G, Stehle, T. 登録日 2012-03-28 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase. Plos One, 7, 2012
3FYD	Crystal Structure of Dim1 from the thermophilic archeon, Methanocaldococcus jannaschi 分子名称: Probable dimethyladenosine transferase, SULFATE ION 著者 Scarsdale, J.N, Musayev, F.N, Rife, J.P. 登録日 2009-01-22 公開日 2009-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases. J.Mol.Biol., 391, 2009
1QJA	14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2) 分子名称: 14-3-3 PROTEIN ZETA, PHOSPHOPEPTIDE 著者 Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B. 登録日 1999-06-23 公開日 1999-09-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding Mol.Cell, 4, 1999
4V9Q	Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A. 登録日 2013-06-12 公開日 2014-07-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 110, 2013
4UQZ	Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes 分子名称: ACETATE ION, HSIB1, HSIE1 著者 Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. 登録日 2014-06-25 公開日 2014-10-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes. RNA, 20, 2014
3JAJ	Structure of the engaged state of the mammalian SRP-ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Voorhees, R.M, Hegde, R.S. 登録日 2015-06-16 公開日 2015-08-05 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structures of the scanning and engaged states of the mammalian SRP-ribosome complex. Elife, 4, 2015
1QJ7	Novel Covalent Active Site Thrombin Inhibitors 分子名称: 6-CARBAMIMIDOYL-2-[5-(3-DIETHYLCARBAMOYL-PHENYL)-2-HYDROXY-INDAN-1-YL]-HEXANOIC ACID, HIRUGEN, THROMBIN 著者 Jhoti, H, Cleasby, A. 登録日 1999-06-22 公開日 2000-06-22 最終更新日 2018-05-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Thrombin Complexed to a Novel Series of Synthetic Inhibitors Containing a 5,5-Trans-Lactone Template Biochemistry, 38, 1999
3K3Q	Crystal Structure of a Llama Antibody complexed with the C. Botulinum Neurotoxin Serotype A Catalytic Domain 分子名称: Botulinum neurotoxin type A, ZINC ION, llama Aa1 VHH domain 著者 Thompson, A.A, Dong, J, Marks, J.D, Stevens, R.C. 登録日 2009-10-04 公開日 2010-02-23 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic alpha-Exosite Binding Region. J.Mol.Biol., 397, 2010
3JCG	Cryo-EM structure of the magnesium channel CorA in the magnesium-free, asymmetric open state I 分子名称: Magnesium transport protein CorA 著者 Matthies, D, Perozo, E, Subramaniam, S. 登録日 2015-12-11 公開日 2016-02-17 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7.06 Å) 主引用文献 Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating. Cell(Cambridge,Mass.), 164, 2016
3K4O	Crystal Structure of Isopentenyl Phosphate Kinase from Methanocaldococcus jannaschii 分子名称: MERCURY (II) ION, SULFATE ION, isopentenyl phosphate kinase 著者 Dellas, N, Noel, J.P. 登録日 2009-10-05 公開日 2010-05-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates. Acs Chem.Biol., 5, 2010
7A23	Plant mitochondrial respiratory complex I 分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... 著者 Soufari, H, Waltz, F, Hashem, Y. 登録日 2020-08-15 公開日 2020-10-28 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM. Nat Commun, 11, 2020
4V6B	Crystal structure of human ferritin Phe167SerfsX26 mutant. 分子名称: CALCIUM ION, Ferritin 著者 Hurley, T.D, Vidal, R. 登録日 2009-06-19 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration J.Biol.Chem., 285, 2010
1QRP	Human pepsin 3A in complex with a phosphonate inhibitor IVA-VAL-VAL-LEU(P)-(O)PHE-ALA-ALA-OME 分子名称: PEPSIN 3A, methyl N-[(2S)-2-({(S)-hydroxy[(1R)-3-methyl-1-{[N-(3-methylbutanoyl)-L-valyl-L-valyl]amino}butyl]phosphoryl}oxy)-3-phenylpropanoyl]-L-alanyl-L-alaninate 著者 Fujinaga, M, Cherney, M.M, Tarasova, N.I, Bartlett, P.A, Hanson, J.E, James, M.N.G. 登録日 1999-06-15 公開日 1999-06-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural study of the complex between human pepsin and a phosphorus-containing peptidic -transition-state analog. Acta Crystallogr.,Sect.D, 56, 2000
4W8I	Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase 分子名称: Probable sphingosine-1-phosphate lyase 著者 Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2014-08-24 公開日 2014-11-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy. Proc.Natl.Acad.Sci.USA, 113, 2016
4WA8	Methanopyrus Kandleri FEN-1 nuclease 分子名称: CHLORIDE ION, Flap endonuclease 1 著者 Shah, S, Dunten, P, Horton, N.C. 登録日 2014-08-28 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and specificity of FEN-1 from Methanopyrus kandleri. Proteins, 83, 2015
1QP2	SOLUTION STRUCTURE OF PHOTOSYSTEM I ACCESSORY PROTEIN E FROM THE CYANOBACTERIUM NOSTOC SP. STRAIN PCC 8009 分子名称: PROTEIN (PSAE PROTEIN) 著者 Mayer, K.L, Shen, G, Bryant, D.A, Lecomte, J.T.J, Falzone, C.J. 登録日 1999-05-29 公開日 1999-10-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The solution structure of photosystem I accessory protein E from the cyanobacterium Nostoc sp. strain PCC 8009. Biochemistry, 38, 1999
3JS5	Crystal structure of protein tyrosine phosphatase from Entamoeba histolytica with Hepes in the active site. High resolution, alternative crystal form with 1 molecule in asymmetric unit 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase, SODIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-09-09 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Mol.Biochem.Parasitol., 193, 2014
3JSJ	Crystal structure of a putative tetr-transcriptional regulator (sav143) from streptomyces avermitilis ma-4680 at 2.10 A resolution 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Putative TetR-family transcriptional regulator 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-09-10 公開日 2009-09-22 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of Putative transcriptional regulator (NP_821317.1) from Streptomyces avermitilis MA-4680 at 2.10 A resolution To be published

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