Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1QRP

Human pepsin 3A in complex with a phosphonate inhibitor IVA-VAL-VAL-LEU(P)-(O)PHE-ALA-ALA-OME

Summary for 1QRP
Entry DOI10.2210/pdb1qrp/pdb
Related PRD IDPRD_000657
DescriptorPEPSIN 3A, methyl N-[(2S)-2-({(S)-hydroxy[(1R)-3-methyl-1-{[N-(3-methylbutanoyl)-L-valyl-L-valyl]amino}butyl]phosphoryl}oxy)-3-phenylpropanoyl]-L-alanyl-L-alaninate (3 entities in total)
Functional Keywordsaspartic proteinase, phosphonate inhibitor, transition state analogue, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight35385.75
Authors
Fujinaga, M.,Cherney, M.M.,Tarasova, N.I.,Bartlett, P.A.,Hanson, J.E.,James, M.N.G. (deposition date: 1999-06-15, release date: 1999-06-18, Last modification date: 2012-12-12)
Primary citationFujinaga, M.,Cherney, M.M.,Tarasova, N.I.,Bartlett, P.A.,Hanson, J.E.,James, M.N.
Structural study of the complex between human pepsin and a phosphorus-containing peptidic -transition-state analog.
Acta Crystallogr.,Sect.D, 56:272-279, 2000
Cited by
PubMed: 10713513
DOI: 10.1107/S0907444999016376
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.96 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon