4V6B

Crystal structure of human ferritin Phe167SerfsX26 mutant.

This is a non-PDB format compatible entry.

Summary for 4V6B

• Entry DOI: 10.2210/pdb4v6b/pdb
• Descriptor: Ferritin, CALCIUM ION (3 entities in total)
• Functional Keywords: iron storage protein, disorder, iron, iron storage, metal-binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 144
• Total formula weight: 3095371.92

Authors

Hurley, T.D.,Vidal, R. (deposition date: 2009-06-19, release date: 2014-07-09, Last modification date: 2023-09-20)

• Primary citation: Baraibar, M.A.,Muhoberac, B.B.,Garringer, H.J.,Hurley, T.D.,Vidal, R.; Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration; J.Biol.Chem., 285:1950-1956, 2010; PubMed: 19923220; DOI: 10.1074/jbc.M109.042986

Experimental method

X-RAY DIFFRACTION (2.85 Å)