3JS5

Crystal structure of protein tyrosine phosphatase from Entamoeba histolytica with Hepes in the active site. High resolution, alternative crystal form with 1 molecule in asymmetric unit

Summary for 3JS5

Entry DOI	10.2210/pdb3js5/pdb
Related	3IDO 3ILY
Descriptor	Protein tyrosine phosphatase, SODIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	niaid, ssgcid, seattle structural genomics center for infectious disease, parasitic protozoan, dysentery, phosphotyrosine, phosphatase, hydrolase
Biological source	Entamoeba histolytica
Total number of polymer chains	1
Total formula weight	20643.55
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2009-09-09, release date: 2009-09-22, Last modification date: 2023-09-06)
Primary citation	Linford, A.S.,Jiang, N.M.,Edwards, T.E.,Sherman, N.E.,Van Voorhis, W.C.,Stewart, L.J.,Myler, P.J.,Staker, B.L.,Petri, W.A. Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Mol.Biochem.Parasitol., 193:33-44, 2014 Cited by PubMed: 24548880 DOI: 10.1016/j.molbiopara.2014.01.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.94 Å)

Structure validation