8JV4
 
 | |
8JV3
 | |
8JV2
 | |
8JV1
 | |
8JUU
 | | rat megalin | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A. | | 登録日 | 2023-06-27 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
8JUT
 | | rat megalin RAP complex | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A. | | 登録日 | 2023-06-27 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
8JUO
 | |
8JUK
 | |
8JUG
 | | Crystal structure of human MMP-7 in complex with inhibitor | | 分子名称: | CALCIUM ION, Matrilysin, Peptide Inhibitor, ... | | 著者 | Kamitani, M, Abe-Sato, K, Oka, Y. | | 登録日 | 2023-06-26 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis.
J.Med.Chem., 66, 2023
|
|
8JU6
 | | Structure of human TRPV4 with antagonist GSK279 | | 分子名称: | 1-({(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl}methyl)-1H-benzimidazole-6-carbonitrile, Transient receptor potential cation channel subfamily V member 4,3C-GFP | | 著者 | Fan, J, Lei, X. | | 登録日 | 2023-06-24 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural Pharmacology of TRPV4 Antagonists.
Adv Sci, 2024
|
|
8JTM
 | | CNE55.664 trimer in complex with broadly neutralizing HIV antibody PGT145 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PGT145 antibody fragment, ... | | 著者 | Chatterjee, A, Chen, C, Lee, K, Mangala Prasad, V. | | 登録日 | 2023-06-22 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (5.14 Å) | | 主引用文献 | An HIV-1 broadly neutralizing antibody overcomes structural and dynamic variation through highly focused epitope targeting.
Npj Viruses, 1, 2023
|
|
8JTD
 | | BJOX2000.664 trimer in complex with Fab fragment of broadly neutralizing HIV antibody PGT145 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PGT145 antibody fragment, ... | | 著者 | Chatterjee, A, Chen, C, Lee, K, Mangala Prasad, V. | | 登録日 | 2023-06-21 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | An HIV-1 broadly neutralizing antibody overcomes structural and dynamic variation through highly focused epitope targeting.
Npj Viruses, 1, 2023
|
|
8JT6
 | | 5-HT1A-Gi in complex with compound (R)-IHCH-7179 | | 分子名称: | 1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Chen, Z, Xu, P, Huang, S, Xu, H.E, Wang, S. | | 登録日 | 2023-06-21 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Flexible scaffold-based cheminformatics approach for polypharmacological drug design.
Cell, 187, 2024
|
|
8JT4
 | |
8JT3
 | | Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Arg | | 分子名称: | (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-arginine, ACETATE ION, CrmG, ... | | 著者 | Su, K, Zhang, Y, Xu, J, Liu, J. | | 登録日 | 2023-06-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Co-crystal structure provides insights on transaminase CrmG recognition amino donor L-Arg.
Biochem.Biophys.Res.Commun., 675, 2023
|
|
8JT1
 | | COLLAGENASE FROM GRIMONTIA (VIBRIO) HOLLISAE 1706B COMPLEXED WITH GLY-PRO-HYP-GLY-PRO-HYP | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-mer peptide, ... | | 著者 | Ueshima, S, Yaskawa, K, Takita, T, Mikami, B. | | 登録日 | 2023-06-21 | | 公開日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insights into the catalytic mechanism of Grimontia hollisae collagenase through structural and mutational analyses.
Febs Lett., 597, 2023
|
|
8JSZ
 | | Crystal structure of a uridylate cyclase from Anabaena sp. | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | 登録日 | 2023-06-20 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal structure of a uridylate cyclase from Anabaena sp.
To Be Published
|
|
8JST
 | |
8JSO
 | | AMPH-bound hTAAR1-Gs protein complex | | 分子名称: | (2S)-1-phenylpropan-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | | 登録日 | 2023-06-20 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1.
Nature, 624, 2023
|
|
8JSD
 | |
8JS9
 | | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | | 著者 | Yamagata, A. | | 登録日 | 2023-06-19 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
|
|
8JS8
 | | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | | 分子名称: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yamagata, A. | | 登録日 | 2023-06-19 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
|
|
8JS7
 | | Dimeric PAS domains of oxygen sensor FixL in complex with imidazole-bound heme | | 分子名称: | GLYCEROL, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Kamaya, M, Koteishi, H, Sawai, H, Sugimoto, H, Shiro, Y. | | 登録日 | 2023-06-19 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Dimeric PAS domains of oxygen sensor FixL in complex with imidazole-bound heme.
To be published
|
|
8JS6
 | | Dimeric PAS domains of oxygen sensor FixL in complex with cyanide-bound ferric heme | | 分子名称: | CYANIDE ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Kamaya, M, Koteishi, H, Sawai, H, Sugimoto, H, Shiro, Y. | | 登録日 | 2023-06-19 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Dimeric PAS domains of oxygen sensor FixL in complex with imidazole-bound heme.
To be published
|
|
8JS5
 | | Dimeric PAS domains of oxygen sensor FixL with ferric unliganded heme | | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Sensor protein FixL | | 著者 | Kamaya, M, Koteishi, H, Sawai, H, Sugimoto, H, Shiro, Y. | | 登録日 | 2023-06-19 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Dimeric PAS domains of oxygen sensor FixL in complex with imidazole-bound heme.
To be published
|
|
