8JUT

rat megalin RAP complex

Summary for 8JUT

• Entry DOI: 10.2210/pdb8jut/pdb
• EMDB information: 36663
• Descriptor: LDL receptor related protein 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (20 entities in total)
• Functional Keywords: endocytosis receptor, endocytosis
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 18
• Total formula weight: 1172517.87

Authors

Goto, S.,Tsutsumi, A.,Lee, Y.,Hosojima, M.,Kabasawa, H.,Komochi, K.,Yun-san, L.,Nagatoshi, S.,Tsumoto, K.,Nishizawa, T.,Kikkawa, M.,Saito, A. (deposition date: 2023-06-27, release date: 2024-06-19)

• Primary citation: Goto, S.,Tsutsumi, A.,Lee, Y.,Hosojima, M.,Kabasawa, H.,Komochi, K.,Nagatoishi, S.,Takemoto, K.,Tsumoto, K.,Nishizawa, T.,Kikkawa, M.,Saito, A.; Cryo-EM structures elucidate the multiligand receptor nature of megalin.; Proc.Natl.Acad.Sci.USA, 121:e2318859121-e2318859121, 2024; PubMed: 38771880; DOI: 10.1073/pnas.2318859121

Experimental method

ELECTRON MICROSCOPY (4.2 Å)