8JT6
5-HT1A-Gi in complex with compound (R)-IHCH-7179
Summary for 8JT6
Entry DOI | 10.2210/pdb8jt6/pdb |
EMDB information | 36634 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16, ... (9 entities in total) |
Functional Keywords | serotonin receptor, 5-ht1ar, gi-protein, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 178793.33 |
Authors | |
Primary citation | Chen, Z.,Yu, J.,Wang, H.,Xu, P.,Fan, L.,Sun, F.,Huang, S.,Zhang, P.,Huang, H.,Gu, S.,Zhang, B.,Zhou, Y.,Wan, X.,Pei, G.,Xu, H.E.,Cheng, J.,Wang, S. Flexible scaffold-based cheminformatics approach for polypharmacological drug design. Cell, 187:2194-2208.e22, 2024 Cited by PubMed: 38552625DOI: 10.1016/j.cell.2024.02.034 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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