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5EEY
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RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 11.6 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
8WXR
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BU of 8wxr by Molmil
Structure of WDR5 in complex with WIN motif containing MBD3C F47A
分子名称: MBD3C, WD repeat-containing protein 5
著者Xu, L, Yang, Y.
登録日2023-10-30
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.
J.Biol.Chem., 300, 2024
4KWF
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BU of 4kwf by Molmil
Crystal Structure Analysis of ALDH2+ALDiB33
分子名称: 1,2-ETHANEDIOL, 1-benzyl-1H-indole-2,3-dione, Aldehyde dehydrogenase, ...
著者Hurley, T.D, Kimble-Hill, A.C.
登録日2013-05-24
公開日2014-04-09
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones.
J.Med.Chem., 57, 2014
2V59
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BU of 2v59 by Molmil
CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2
分子名称: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE
著者Mochalkin, I, Miller, J.R.
登録日2008-10-02
公開日2009-01-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2C0G
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BU of 2c0g by Molmil
Structure of PDI-related Chaperone, Wind mutant-Y53S
分子名称: CHLORIDE ION, SODIUM ION, WINDBEUTEL PROTEIN
著者Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M.
登録日2005-09-02
公開日2006-08-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants.
Acta Crystallogr.,Sect.D, 62, 2006
2BXF
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BU of 2bxf by Molmil
Human serum albumin complexed with diazepam
分子名称: 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, SERUM ALBUMIN
著者Ghuman, J, Zunszain, P.A, Petitpas, I, Bhattacharya, A.A, Curry, S.
登録日2005-07-26
公開日2005-09-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
J.Mol.Biol., 353, 2005
3CUE
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BU of 3cue by Molmil
Crystal structure of a TRAPP subassembly activating the Rab Ypt1p
分子名称: GTP-binding protein YPT1, PALMITIC ACID, Transport protein particle 18 kDa subunit, ...
著者Cai, Y, Reinisch, K.M.
登録日2008-04-16
公開日2008-07-08
最終更新日2012-03-21
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes.
Cell(Cambridge,Mass.), 133, 2008
3C6P
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BU of 3c6p by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
分子名称: (2S)-2-(1H-indol-3-yl)pentanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
著者Tan, X.
登録日2008-02-04
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
5EGQ
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BU of 5egq by Molmil
Structure of tetrameric rat phenylalanine hydroxylase mutant R270K, residues 25-453
分子名称: Phenylalanine-4-hydroxylase, SULFATE ION
著者Taylor, A.B, Khan, C.A, Fitzpatrick, P.F.
登録日2015-10-27
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.
J.Am.Chem.Soc., 138, 2016
4GX1
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BU of 4gx1 by Molmil
Crystal structure of the GsuK bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ...
著者Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y.
登録日2012-09-03
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
2C16
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BU of 2c16 by Molmil
5-(4-Carboxy-2-oxo-butane-1-sulfinyl)-4-oxo-pentanoic acid acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa
分子名称: CHLORIDE ION, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, DI(HYDROXYETHYL)ETHER, ...
著者Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N.
登録日2005-09-11
公開日2006-06-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
5AOP
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BU of 5aop by Molmil
SULFITE REDUCTASE STRUCTURE REDUCED WITH CRII EDTA, 5-COORDINATE SIROHEME, SIROHEME FEII, [4FE-4S] +1
分子名称: IRON/SULFUR CLUSTER, POTASSIUM ION, SIROHEME, ...
著者Crane, B.R, Getzoff, E.D.
登録日1997-07-10
公開日1998-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of the siroheme- and Fe4S4-containing active center of sulfite reductase in different states of oxidation: heme activation via reduction-gated exogenous ligand exchange.
Biochemistry, 36, 1997
2V6A
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BU of 2v6a by Molmil
Crystal structure of Chlamydomonas reinhardtii Rubisco with large- subunit mutations V331A, G344S
分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ...
著者Karkehabadi, S, Satagopan, S, Taylor, T.C, Spreitzer, R.J, Andersson, I.
登録日2007-07-14
公開日2007-07-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Analysis of Altered Large-Subunit Loop-6-Carboxy-Terminus Interactions that Influence Catalytic Efficiency and Co2-O2 Specificity of Ribulose-1,5-Bisphosphate Carboxylase Oxygenase
Biochemistry, 46, 2007
3CWZ
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BU of 3cwz by Molmil
Structure of RAB6(GTP)-R6IP1 complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab6-interacting protein 1, ...
著者Recacha, R, Houdusse, A, Goud, B, Khan, A.R.
登録日2008-04-23
公開日2008-11-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.
Structure, 17, 2009
2C2R
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BU of 2c2r by Molmil
Efficient and High Fidelity Incorporation of dCTP Opposite 7,8- Dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA Polymerase Dpo4
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*C)-3', 5'-D(*TP*CP*AP*C 8OGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ...
著者Irimia, A, Loukachevitch, L.V, Egli, M.
登録日2005-09-29
公開日2005-11-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Efficient and High Fidelity Incorporation of Dctp Opposite 7,8-Dihydro-8-Oxodeoxyguanosine by Sulfolobus Solfataricus DNA Polymerase Dpo4
J.Biol.Chem., 281, 2006
8WXV
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Structure of WDR5 in complex with WIN motif containing SET1B
分子名称: SET1B, WD repeat-containing protein 5
著者Xu, L, Yang, Y.
登録日2023-10-30
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.
J.Biol.Chem., 300, 2024
2BEO
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BU of 2beo by Molmil
PrfA, Transcriptional Regulator In Listeria Monocytogenes
分子名称: ACETAMIDE, CHLORIDE ION, GLUTAMINE, ...
著者Eiting, M, Hagelueken, G, Schubert, W.-D, Heinz, D.W.
登録日2004-11-26
公開日2005-04-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Mutation G145S in Prfa, a Key Virulence Regulator of Listeria Monocytogenes, Increases DNA-Binding Affinity by Stabilizing the Hth Motif
Mol.Microbiol., 56, 2005
7KFG
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BU of 7kfg by Molmil
Antibody Fab BDBV-289
分子名称: Antibody Fab BDBV-289 heavy chain, Antibody Fab BDBV-289 light chain, DI(HYDROXYETHYL)ETHER
著者Murin, C.D, Bruhn, J.F, Ward, A.B.
登録日2020-10-13
公開日2021-04-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
3C9A
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BU of 3c9a by Molmil
High Resolution Crystal Structure of Argos bound to the EGF domain of Spitz
分子名称: BROMIDE ION, Protein giant-lens, Protein spitz
著者Klein, D.E, Stayrook, S.E, Shi, F, Narayan, K, Lemmon, M.A.
登録日2008-02-15
公開日2008-05-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for EGFR ligand sequestration by Argos.
Nature, 453, 2008
2BS9
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BU of 2bs9 by Molmil
Native crystal structure of a GH39 beta-xylosidase XynB1 from Geobacillus stearothermophilus
分子名称: BETA-XYLOSIDASE, CALCIUM ION
著者Czjzek, M, Bravman, T, Henrissat, B, Shoham, Y.
登録日2005-05-19
公開日2005-10-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Enzyme-Substrate Complex Structures of a Gh39 Beta-Xylosidase from Geobacillus Stearothermophilus.
J.Mol.Biol., 353, 2005
7L5I
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BU of 7l5i by Molmil
Crystal Structure of Haemophilus influenzae MtsZ at pH 7.0
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Struwe, M.A, Luo, Z, Kappler, U, Kobe, B.
登録日2020-12-22
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.733 Å)
主引用文献Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes.
J.Biol.Chem., 296, 2021
5EKW
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BU of 5ekw by Molmil
A. thaliana IGPD2 in complex with the racemate of the triazole-phosphonate inhibitor, C348
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W.
登録日2015-11-04
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
Angew.Chem.Int.Ed.Engl., 55, 2016
4H1Z
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Crystal structure of putative isomerase from Sinorhizobium meliloti, open loop conformation (target EFI-502104)
分子名称: CHLORIDE ION, Enolase Q92Zs5, FORMIC ACID, ...
著者Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-09-11
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献Crystal Structure of Enolase Q92Zs5 (Target EFI-502104) from Sinorhizobium meliloti
To be Published
5EI3
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Co-crystal structure of eIF4E with nucleotide mimetic inhibitor.
分子名称: Eukaryotic translation initiation factor 4 gamma, Eukaryotic translation initiation factor 4E, SULFATE ION, ...
著者Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M.
登録日2015-10-29
公開日2016-09-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation.
Eur.J.Med.Chem., 124, 2016
5CYU
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Structure of the soluble domain of EccB1 from the Mycobacterium smegmatis ESX-1 secretion system.
分子名称: Conserved membrane protein
著者Arbing, M.A, Chan, S, Kahng, S, Kim, J, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-07-30
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016

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