3C9A

High Resolution Crystal Structure of Argos bound to the EGF domain of Spitz

Summary for 3C9A

Entry DOI	10.2210/pdb3c9a/pdb
Related	3CA7 3CGU
Descriptor	Protein giant-lens, Protein spitz, BROMIDE ION, ... (4 entities in total)
Functional Keywords	argos, spitz, egf, egfr inhibitor, inhibitor, developmental protein, glycoprotein, secreted, sensory transduction, vision, differentiation, egf-like domain, endoplasmic reticulum, golgi apparatus, membrane, neurogenesis, transmembrane, hormone-signaling protein complex, hormone/signaling protein
Biological source	Drosophila melanogaster (Fruit fly) More
Cellular location	Secreted : Q00805 Cell membrane ; Single-pass type I membrane protein : Q01083
Total number of polymer chains	4
Total formula weight	64702.27
Authors	Klein, D.E.,Stayrook, S.E.,Shi, F.,Narayan, K.,Lemmon, M.A. (deposition date: 2008-02-15, release date: 2008-05-20, Last modification date: 2017-10-25)
Primary citation	Klein, D.E.,Stayrook, S.E.,Shi, F.,Narayan, K.,Lemmon, M.A. Structural basis for EGFR ligand sequestration by Argos. Nature, 453:1271-1275, 2008 Cited by PubMed: 18500331 DOI: 10.1038/nature06978 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation