5EKW

A. thaliana IGPD2 in complex with the racemate of the triazole-phosphonate inhibitor, C348

Summary for 5EKW

Entry DOI	10.2210/pdb5ekw/pdb
Descriptor	Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, [(2S)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid, ... (8 entities in total)
Functional Keywords	herbicide development, histidine biosynthesis, inhibitor complex, dehydratase, lyase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	1
Total formula weight	23567.40
Authors	Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W. (deposition date: 2015-11-04, release date: 2016-10-05, Last modification date: 2024-01-10)
Primary citation	Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W. Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide. Angew.Chem.Int.Ed.Engl., 55:13485-13489, 2016 Cited by PubMed: 27717128 DOI: 10.1002/anie.201607185 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation